24617-03-6

Basic information

• Product Name: 6-chloro-2-[2'-deoxy-3',5'-di-O-(4-methylbenzoyl)-α-D-erythro-pentofuranosyl]pyridazin-3(2H)-one
• CAS NO: 24617-03-6
• Molecular Weight: 482.92
• Mol File: 24617-03-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-chloro-2-[2'-deoxy-3',5'-di-O-(4-methylbenzoyl)-α-D-erythro-pentofuranosyl]pyridazin-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-2-[2'-deoxy-3',5'-di-O-(4-methylbenzoyl)-α-D-erythro-pentofuranosyl]pyridazin-3(2H)-one(24617-03-6)
• EPA Substance Registry System: 6-chloro-2-[2'-deoxy-3',5'-di-O-(4-methylbenzoyl)-α-D-erythro-pentofuranosyl]pyridazin-3(2H)-one(24617-03-6)

Safety Data

• Hazardous Substances Data: 24617-03-6(Hazardous Substances Data)

Upstream product

• 19064-67-6 6-chloro-2H-pyridazin-3-one 
• 4330-21-6 2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride 

Relevant articles and documents

Studies on improved synthesis of 2′-deoxyribonucleosides of pyridazine derivatives

A number of 2′-deoxyribonucleosides of halogenated pyridazine derivatives were prepared by glycosylation of their respective potassium or DBU salts in acetone. The reaction yielded predominatly β-anomers that could be purified by simple crystallization or column chromatography. Of the studied pyridazines and deoxynucleosides, only 4-bromo-6-chloro-pyridazin-3-one and 6-chloro-2-(2′-deoxyribofuranosyl)pyridazin-3-one showed modest inhibition of CK2 kinase.