246181-65-7

Basic information

• Product Name: 2-Pyrrolidinone, 1-acetyl-5-fluoro-3-methyl- (9CI)
• Synonyms: 2-Pyrrolidinone, 1-acetyl-5-fluoro-3-methyl- (9CI);1-Acetyl-5-Fluoro-3-Methyl-2-Pyrrolidinone
• CAS NO: 246181-65-7
• Molecular Formula: C7H10FNO2
• Molecular Weight: 159.1582032
• Product Categories: ACETYLGROUP;HALIDE
• Mol File: 246181-65-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 244.5±33.0 °C(Predicted)
• Appearance: /
• Density: 1.19±0.1 g/cm3(Predicted)
• PKA: -4.80±0.60(Predicted)
• CAS DataBase Reference: 2-Pyrrolidinone, 1-acetyl-5-fluoro-3-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrrolidinone, 1-acetyl-5-fluoro-3-methyl- (9CI)(246181-65-7)
• EPA Substance Registry System: 2-Pyrrolidinone, 1-acetyl-5-fluoro-3-methyl- (9CI)(246181-65-7)

Safety Data

• Hazardous Substances Data: 246181-65-7(Hazardous Substances Data)

Relevant articles and documents

Electrochemical direct fluorination of lactams

The electrochemical fluorination of a variety of N-protected lactams was carried out and Et3N-5HF was found to be superior to Et3N-3HF as the electrolyte. When 5-and 6-membered N-acetyl or ethoxycarbonyl lactams were used as substrates, the fluorination reaction selectively took place at the α-position of the lactam nitrogen and the corresponding monofluoro products could be obtained in good yields.