24622-31-9

Basic information

• Product Name: 2-Benzothiazolamine,N-butyl-(9CI)
• Synonyms: 2-Benzothiazolamine,N-butyl-(9CI);N-butyl-1,3-benzothiazol-2-amine
• CAS NO: 24622-31-9
• Molecular Formula: C11H14N2S
• Molecular Weight: 206.30726
• Product Categories: BENZOTHIAZOLE
• Mol File: 24622-31-9.mol
• Article Data: 16

Chemical Properties

• Melting Point: 68 °C
• Boiling Point: 313.5°Cat760mmHg
• Flash Point: 143.4°C
• Appearance: /
• Density: 1.177g/cm³
• Vapor Pressure: 0.000495mmHg at 25°C
• Refractive Index: 1.652
• PKA: 3.49±0.10(Predicted)
• CAS DataBase Reference: 2-Benzothiazolamine,N-butyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzothiazolamine,N-butyl-(9CI)(24622-31-9)
• EPA Substance Registry System: 2-Benzothiazolamine,N-butyl-(9CI)(24622-31-9)

Safety Data

• Hazardous Substances Data: 24622-31-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H14N2S/c1-2-3-8-12-11-13-9-6-4-5-7-10(9)14-11/h4-7H,2-3,8H2,1H3,(H,12,13)

Upstream product

• 6336-01-2 3-n-butyl-1-phenylthiourea 
• 615-43-0 2-iodophenylamine 
• 109-46-6 1,3-dibutylthiourea 
• 149-30-4 2-Mercaptobenzothiazole 
• 109-73-9 N-butylamine 
• 62644-22-8 N-n-Butyl-N'-o-bromphenylthioharnstoff 
• 592-82-5 butyl isothiocyanate 
• 136-95-8 2-amino-benzthiazole 
• 71-36-3 butan-1-ol 
• 2769-64-4 n-butyl isonitrile 
• 137-07-5 2-amino-benzenethiol 
• 615-20-3 2-chlorobenzo[d][1,3]thiazole 
• 103-72-0 phenyl isothiocyanate 
• 99982-06-6 n-butanal N-tosylhydrazone 

Relevant articles and documents

Ionic Reactivity of 2-Isocyanoaryl Thioethers: Access to 2-Halo and 2-Aminobenzothia/Selenazoles

An ionic cascade insertion/cyclization reaction of thia-/selena-functionalized arylisocyanides has been successfully developed for the efficient and practical synthesis of 2-halobenzothiazole/benzoselenazole derivatives. This synthetic protocol, incorporating a halogen atom when forming the five-membered ring of benzothia/selenazoles, is different from the existing ones, where halogenation of the preformed benzothia/selenazole precursors happens. Additionally, a facile access to 2-aminobenzothiazoles is also achieved by the one-pot cascade reaction of 2-isocyanoaryl thioethers, iodine, and amines.

Method for synthesizing benzothiazole by microwave radiation of benzothioamide compound in aqueous phase

The invention discloses a method for synthesizing benzothiazole by microwave radiation of a benzothioamide compound in an aqueous phase. The method includes the steps: adding the benzothioamide compound into the aqueous phase under microwave conditions; performing cyclization under alkaline conditions to generate the benzothiazole. The method for preparing the benzothiazole is environmentally friendly, simple and convenient in operation, safe, cheap and efficient. Compared with the prior art, the method is applicable to a lot of functional groups, high in yield, few in by-products, simple in operation, safe, low in cost and environmentally friendly.

Synthesis method of 2-aminobenzothiazole compounds

The invention discloses a preparation method of 2-aminobenzothiazole compounds. The 2-aminobenzothiazole compounds is prepared from the following steps of dissolving phenyl/naphthalene isothiocyanateand primary amine into a solvent, adding a catalyst iodine and an oxidant, carrying out one-pot multi-step tandem reaction to prepare the 2-aminobenzothiazole compounds under the temperature of 80 to 150 DEG C. The synthesis method has the advantages that raw materials are cheap and easily available, the reaction condition is mild, the substrate application range is broad, atom economy is high, requirements of green chemical are met, and a novel method which is economical and practical and green and environmentally friendly is provided for synthesis of the 2-aminobenzothiazole compounds.