24639-11-0

Basic information

• Product Name: N-hippuroyl-alanine
• Synonyms: N-hippuroyl-alanine
• CAS NO: 24639-11-0
• Molecular Weight: 250.254
• Mol File: 24639-11-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: N-hippuroyl-alanine(CAS DataBase Reference)
• NIST Chemistry Reference: N-hippuroyl-alanine(24639-11-0)
• EPA Substance Registry System: N-hippuroyl-alanine(24639-11-0)

Safety Data

• Hazardous Substances Data: 24639-11-0(Hazardous Substances Data)

Upstream product

• 1199-01-5 2-phenylazlactone 
• 302-72-7 rac-Ala-OH 
• 57461-31-1 hippuroyl azide 
• 6330-48-9 N-benzoyl-thioglycine 
• 3101-11-9 Bz-Gly-ONPh 
• 495-69-2 Hippuric Acid 
• 56-41-7 L-alanin 
• 2078-24-2 hippuric acid trimethylsilanyl ester 
• 3695-73-6 glycyl-L-alanine 
• 98-88-4 benzoyl chloride 
• 2979-54-6 phenyl hippurate 
• 52-90-4 L-Cysteine 
• 1235544-18-9 C₂₆H₃₃N₃O₅S₂ 
• 1235544-12-3 C₂₇H₃₅N₃O₆S₂ 

Downstream Products

• 1089175-90-5 N-propyl-[N'-benzoylglycyl-L-alanylglycyl]-L-alanine amide 
• 1089175-92-7 N-hexyl-[N'-benzoylglycyl-L-alanylglycyl]-L-alanine amide 
• 1089175-94-9 N-dodecyl-[N'-benzoylglycyl-L-alanylglycyl]-L-alanine amide 
• 63203-23-6 N-(N-benzoyl-glycyl)-alanine hydrazide 
• 24639-12-1 N-(N-benzoyl-glycyl)-alanine ethyl ester 
• 108489-31-2 N-(N-benzoyl-glycyl)-alanine methyl ester 
• 1499-53-2 ethyl hippurate 

Relevant articles and documents

Phenolic ester mediated oligopeptide synthesis promoted by HOBt

Although substituted phenolic ester mediated peptide synthesis is an efficient and well established method, the same via totally unsubstituted phenyl ester is not preferred due to the extremely slow rate of aminolysis. We have investigated the scope of the unsubstituted phenyl ester as an intermediate in peptide bond formation and found that it may be useful for the design of chemoselective peptide ligation when HOBt is used as an acyl transfer catalyst. The scope of HOBt catalyzed, oxo ester mediated ligation is explored for the synthesis of oligopeptides containing a cysteine, serine and threonine at the N-terminus of the ligating peptide.

Biomimetic self-assembly of tetrapeptides into fibrillar networks and organogels

The self-assembly features of a family of tetrapeptides with a silk-inspired structure are presented. An exhaustive study of the influence of the terminal alkyl chain length in this process is undertaken. Scanning electron microscopy (SEM), wide-angle X-ray diffraction (WAXD), FTIR spectroscopy, and circular dichroism were used for structural analysis. These compounds, as in the natural model, self-assemble into antiparallel β-sheet structures that further organize to form fibrillar aggregates. Furthermore, some of them are capable of forming a crowded network that entraps the solvent leading to physical gels with different microscopic morphologies. A model for the assembly process is proposed. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.

Composition containing a penem or carbapenem antibiotic and the use of the same

Administration of an N-acylated amino acid in association with a penem or carbapenem antibiotic relieves or eliminates the renal problems associated with administration of the antibiotic alone. The amino acid derivative and antibiotic may be formulated together as a composition or administered separately, either simultaneously or sequentially.