2465-93-2

Basic information

• Product Name: 1,2,3-TRIS(2-CYANOETHOXY)PROPANE
• Synonyms: 3,3',3''-[1,2,3-Propanetriyltris(oxy)]tris(propanenitrile);1,2,3-Tris(2-cyanoethoxy)propane,85%,tech.;3,3’,3’’-[1,2,3-propanetriyltris(oxy)]tris-propanenitril;TIMTEC-BB SBB007767;GLYCEROL TRIS(2-CYANOETHYL) ETHER;3,3',3''-(1,2,3-PROPANETRIYLTRIOXY)TRIPROPIONITRILE;3,3',3''-(GLYCERYLTRIOXY)TRIPROPIONITRILE;1,2,3-TRIS(2-CYANOETHOXY)PROPANE
• CAS NO: 2465-93-2
• Molecular Formula: C₁₂H₁₇N₃O₃
• Molecular Weight: 251.28
• EINECS: 219-573-5
• Product Categories: Dinitriles & Trinitriles;Trinitriles;Gas Chromatography;Packed GC;Stationary Phases
• Mol File: 2465-93-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 394.44°C (rough estimate)
• Flash Point: >93.33 °C
• Appearance: /Liquid
• Density: 1.11
• Refractive Index: 1.4600 to 1.4640
• Water Solubility: Soluble in water.
• CAS DataBase Reference: 1,2,3-TRIS(2-CYANOETHOXY)PROPANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3-TRIS(2-CYANOETHOXY)PROPANE(2465-93-2)
• EPA Substance Registry System: 1,2,3-TRIS(2-CYANOETHOXY)PROPANE(2465-93-2)

Safety Data

• Safety Statements: 24/25
• RIDADR: UN3276
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: II
• Hazardous Substances Data: 2465-93-2(Hazardous Substances Data)

Usage

Description

1,2,3-Tris(2-cyanoethoxy)propane, also known as TRIS, is a clear colorless viscous liquid with unique chemical properties. It is a versatile compound that finds applications in various industries due to its distinct characteristics.

Uses

Used in Chemical Analysis:
1,2,3-Tris(2-cyanoethoxy)propane is used as the stationary phase in gas-liquid chromatography for the separation and analysis of volatile compounds. Its chemical properties allow for efficient and accurate identification of different components in a mixture.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1,2,3-Tris(2-cyanoethoxy)propane serves as a key component in the formulation of various drugs. Its compatibility with a wide range of substances makes it an ideal candidate for drug development and delivery.
Used in Polymer Industry:
1,2,3-Tris(2-cyanoethoxy)propane is used as a monomer in the synthesis of polymers. Its unique structure contributes to the development of polymers with specific properties, such as improved strength, flexibility, and durability.
Used in Cosmetics Industry:
In the cosmetics industry, 1,2,3-Tris(2-cyanoethoxy)propane is used as an ingredient in various formulations due to its ability to improve the texture, consistency, and stability of products.
Used in Environmental Applications:
1,2,3-Tris(2-cyanoethoxy)propane is employed in environmental applications, such as the treatment of wastewater and soil remediation, due to its ability to interact with pollutants and facilitate their removal.
Overall, 1,2,3-Tris(2-cyanoethoxy)propane is a versatile compound with a wide range of applications across different industries, making it an essential component in various processes and products.

Upstream product

• 124-41-4 sodium methylate 
• 107-13-1 acrylonitrile 
• 56-81-5 glycerol 

Relevant articles and documents

Free-solvent Michael addition of glycerol to acrylic compounds

In this paper, we report the study of the free-solvent nucleophilic addition of alcohols and glycerol to acrylic compounds, in the presence of catalytic bases. With acrylates, Michael addition and transesterification are in competition: only the PTC reaction with t-butyl acrylate gave trifunctionalized glycerol. With acrylonitrile, the cyanoethylation of glycerol varies with catalysts, temperature, time of reactions and amounts of acrylonitrile. Mono functionalisation of glycerol can be obtained in 28% yield. The optimization of the free-solvent Michael addition of glycerol to acrylonitrile (3.4 equiv., 4 mol% NaOH, 5 h) leads to TCEG (tricyanoethylglycerol, 88% yield, 99% purity) without HCl neutralisation, chlorinated solvents or purification (chromatography or distillation). TCEG can be used as a prochiral core of G0.5 dendrimers.