24654-07-7

Basic information

• Product Name: 2,3-dibromo-3-(2-chloro-phenyl)-propionic acid
• Synonyms: 2,3-dibromo-3-(2-chloro-phenyl)-propionic acid
• CAS NO: 24654-07-7
• Molecular Weight: 342.414
• Mol File: 24654-07-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2,3-dibromo-3-(2-chloro-phenyl)-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dibromo-3-(2-chloro-phenyl)-propionic acid(24654-07-7)
• EPA Substance Registry System: 2,3-dibromo-3-(2-chloro-phenyl)-propionic acid(24654-07-7)

Safety Data

• Hazardous Substances Data: 24654-07-7(Hazardous Substances Data)

Upstream product

• 3752-25-8 o-chlorocinnamic acid 
• 704-96-1 (Z)-3-(2-chlorophenyl)acrylic acid 
• 7726-95-6 bromine 
• 704-96-1 trans-2-chlorocinnamic acid 
• 89-98-5 2-chloro-benzaldehyde 
• 64-19-7 acetic acid 

Downstream Products

• 880142-94-9 α-bromo-2-chloro-cis-cinnamic acid 
• 187463-09-8 (Z)-1-(2-bromovinyl)-2-chlorobenzene 
• 1345842-04-7 4-(2-chlorophenyl)-1-(4-methylphenyl)-1,2,3-triazole 
• 1607020-78-9 N-(4-methylphenyl)-3-exo-(2-chlorobenzylidene)tricyclo[3.2.1.02,4]octane-6,7-endo-dicarboximide 
• 873-31-4 2-chlorophenylacetylene 
• 333309-74-3 (E)-1-(2'-chlorophenyl)-2-bromoethylene 
• 76557-95-4 (Z)-1-(2-bromovinyl)-3-chlorobenzene 
• 3752-25-8 o-chlorocinnamic acid 

Relevant articles and documents

Palladium(0)-Catalyzed Methylcyclopropanation of Norbornenes with Vinyl Bromides and Mechanism Study

An unusual methylcyclopropanation from [2 + 1] cycloadditions of vinyl bromides to norbornenes catalyzed by Pd(OAc)2/PPh3 in the presence of CH3ONa and CH3OH has been established. A methylcyclopropane subunit was installed by a 3-fold domino procedure involving a key protonation course. Preliminary deuterium-labeling studies revealed that the proton came from methyl of CH3OH and also exposed an additional hydrogen/deuterium exchange process. These two proton-concerned reactions were fully chemoselective.

Convenient synthesis of terminal alkynes from anti-3-aryl-2,3- dibromopropanoic acids using a K2CO3/DMSO system

A convenient, efficient, and generally applicable method was developed for the synthesis of terminal alkynes from anti-3-aryl-2,3-dibromopropanoic acids in the presence of DMSO and K2CO3.

Convenient and stereoselective synthesis of (Z)-1-bromo-1-alkenes by microwave-induced reaction

(Z)-1-Bromo-1-alkenes were stereoselectively prepared in high yields in a short reaction time (0.2-1.0 min) by microwave irradiation of the corresponding 2,3-dibromoalkanoic acids in DMF in the presence of triethylamine.