246545-07-3

Basic information

• Product Name: 3-nitro-benzenesulfonic acid-[2-(1⁽³⁾H-imidazol-4-yl)-ethylamide]
• CAS NO: 246545-07-3
• Molecular Weight: 296.307
• Mol File: 246545-07-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-nitro-benzenesulfonic acid-[2-(1⁽³⁾H-imidazol-4-yl)-ethylamide](CAS DataBase Reference)
• NIST Chemistry Reference: 3-nitro-benzenesulfonic acid-[2-(1⁽³⁾H-imidazol-4-yl)-ethylamide](246545-07-3)
• EPA Substance Registry System: 3-nitro-benzenesulfonic acid-[2-(1⁽³⁾H-imidazol-4-yl)-ethylamide](246545-07-3)

Safety Data

• Hazardous Substances Data: 246545-07-3(Hazardous Substances Data)

Upstream product

• 246544-90-1 4,5,6,7-tetrabromo-2-[2-(1-tritylsulfanyl-1H-imidazol-4-yl)-ethyl]-isoindole-1,3-dione 
• 246544-91-2 N-1-tritylsulfenyl-histamine 
• 121-51-7 3-nitrobenzenesulphonyl chloride 
• 51-45-6 histamine 

Relevant articles and documents

Novel carbonic anhydrase isozymes I, II and IV activators incorporating sulfonyl-histamino moieties

Sulfonylamido(ureido) derivatives of histamine were synthesized by an original procedure in order to obtain tight-binding activators of the zinc enzyme carbonic anhydrase (CA), exploiting the binding energy of the alkyl/arylsulfonyl moieties with amino acid residues at the entrance of the active site. In contrast to the lead molecule, histamine, the new derivatives possessed higher affinity for three different CA isozymes, as evidenced by compairing the affinity constants of these compounds for isozyme CA II.