246862-42-0

Basic information

• Product Name: 5,8-Quinolinedione, 6-methoxy-2-phenyl-
• CAS NO: 246862-42-0
• Molecular Formula: C16H11NO3
• Molecular Weight: 265.268
• Mol File: 246862-42-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5,8-Quinolinedione, 6-methoxy-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 5,8-Quinolinedione, 6-methoxy-2-phenyl-(246862-42-0)
• EPA Substance Registry System: 5,8-Quinolinedione, 6-methoxy-2-phenyl-(246862-42-0)

Safety Data

• Hazardous Substances Data: 246862-42-0(Hazardous Substances Data)

Upstream product

• 42065-07-6 2-chloro-6-methoxy-quinoline-5,8-dione 
• 98-80-6 phenylboronic acid 
• 26510-91-8 2,4,5-trimethoxyaniline 
• 14227-14-6 1,2,4-trimethoxy-5-nitrobenzene 
• 4460-86-0 asaraldehyde 
• 42065-10-1 2-chloro-5,6,8-trimethoxyquinoline 
• 152531-86-7 5,6,8-trimethoxyquinoline-2(1H)-one 
• 1335227-01-4 (E)-3-ethoxy-N-(2,4,5-trimethoxyphenyl)acrylamide 

Relevant articles and documents

Novel quinolinequinone antitumor agents: Structure-metabolism studies with NAD(P)H:quinone oxidoreductase (NQO1)

The effects of functional group changes on the metabolism of novel quinolinequinones by recombinant human NAD(P)H:quinone oxidoreductase (NQO1) are described. Overall, the quinolinequinones were much better substrates for NQO1 than analogous indolequinones, with compounds containing heterocyclic substituents at C-2 being among the best substrates.

Quinoline-5,8-dione derivatives for TGase 2 inhibitor, and the pharmaceutical composition comprising the same

The present invention relates to a quinolin-5,8-dione derivative compound represented by chemical formula I, an optical isomer thereof or a pharmaceutically acceptable salt thereof. The compound represented by chemical formula I of the present invention has a TGase 2 inhibitory effect, and the pharmaceutical composition comprising the same can be usefully used for preventing or treating disorders or diseases mediated by TGase 2 or response to TGase 2 inhibition.COPYRIGHT KIPO 2020