246868-68-8Relevant articles and documents
The application of vinylogous iminium salt derivatives to a regiocontrolled and efficient relay synthesis of Lukianol A and related marine natural products
Gupton, John T.,Krumpe, Keith E.,Burnham, Bruce S.,Webb, Tammy M.,Shuford, Jordan S.,Sikorski, James A.
, p. 14515 - 14522 (1999)
Numerous novel pyrrole containing marine natural products have been shown to possess interesting biological properties. These compounds have been the synthetic targets of several research groups and we have previously reported synthetic methods which util
Synthesis of 3,4-diaryl- and 4-acyl-3-arylpyrroles and study of their antimitotic activity
Samet,Sil’yanova,Ushkarov,Semenova,Semenov
, p. 858 - 865 (2018/08/28)
The Barton–Zard reaction of nitro substituted stilbenes and chalcones with ethyl isocyanoacetate afforded 3,4-diaryl- and 4-acyl-3-arylpyrroles, respectively. 3-Arylpyrrole-2,4- dicarboxylates and 4-arylisoxazoline N-oxides were side reaction products. An
Investigations concerning the correlation of COX-1 inhibitory and hydroxyl radical scavenging activity
Scholz, Michael,Ulbrich, Holger,Mattern, Andreas,Kramb, Jan-Peter,Kiefer, Werner,Dannhardt, Gerd
experimental part, p. 281 - 287 (2009/04/04)
The aim was to study the COX-1 inhibiting efficacy in context with hydroxyl radical scavenging properties of compounds bearing a carboxylic acid and ester function, respectively. In general, the acids are more potent radical scavengers than the corresponding esters but there is no clear correlation with their COX-1 inhibiting potencies. A feasible scavenging mechanism of carboxylic acids is discussed.