247114-43-8

Basic information

• Product Name: 3-[3-(1H-benzoimidazol-2-ylsulfanyl)-propoxy]-benzaldehyde
• Synonyms: 3-[3-(1H-benzoimidazol-2-ylsulfanyl)-propoxy]-benzaldehyde
• CAS NO: 247114-43-8
• Molecular Weight: 312.392
• Mol File: 247114-43-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[3-(1H-benzoimidazol-2-ylsulfanyl)-propoxy]-benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[3-(1H-benzoimidazol-2-ylsulfanyl)-propoxy]-benzaldehyde(247114-43-8)
• EPA Substance Registry System: 3-[3-(1H-benzoimidazol-2-ylsulfanyl)-propoxy]-benzaldehyde(247114-43-8)

Safety Data

• Hazardous Substances Data: 247114-43-8(Hazardous Substances Data)

Upstream product

• 100-83-4 meta-hydroxybenzaldehyde 
• 144707-69-7 3-(3'-bromopropyloxy)benzaldehyde 
• 134469-07-1 Benzimidazol-2-thiol 

Relevant articles and documents

α-Cyanocinnamide derivatives: A new family of non-peptide, non-sulfhydryl inhibitors of ras farnesylation

Farnesylation of Ras and other proteins is required for their membrane attachment and normal function. Here we report on the synthesis of α-cyanocinnamide derivatives, a new family of farnesyltransferase inhibitors. These compounds are nonpeptidic and do not contain sulfhydryl groups. The most potent compound is a pure competitive inhibitor with respect to the Ras protein and mixed competitive with respect to farnesyl diphosphate. Selectivity studies against geranylgeranyltransferase and biological activities of selected compounds are described. Copyright (C) 1999.