247237-44-1

Basic information

• Product Name: methyl 3-chloro-2-[N-(3-ethoxycarbonyl)propyl-N-p-toluenesulfonyl]aminobenzoate
• Synonyms: methyl 3-chloro-2-[N-(3-ethoxycarbonyl)propyl-N-p-toluenesulfonyl]aminobenzoate
• CAS NO: 247237-44-1
• Molecular Weight: 453.944
• Mol File: 247237-44-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3-chloro-2-[N-(3-ethoxycarbonyl)propyl-N-p-toluenesulfonyl]aminobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-chloro-2-[N-(3-ethoxycarbonyl)propyl-N-p-toluenesulfonyl]aminobenzoate(247237-44-1)
• EPA Substance Registry System: methyl 3-chloro-2-[N-(3-ethoxycarbonyl)propyl-N-p-toluenesulfonyl]aminobenzoate(247237-44-1)

Safety Data

• Hazardous Substances Data: 247237-44-1(Hazardous Substances Data)

Upstream product

• 42087-81-0 3-chloro-2-nitro-benzoic acid methyl ester 
• 98-59-9 p-toluenesulfonyl chloride 
• 77820-58-7 methyl 3-chloroanthranilate 
• 4771-47-5 3-chloro-2-nitro-benzoic acid 
• 2969-81-5 Ethyl 4-bromobutyrate 
• 247237-41-8 N-p-toluenesulfonyl-3-chloroanthranilic acid methyl ester 

Downstream Products

• 150682-46-5 9-chloro-5-(N-methylamino)-1-[4-[(2-methylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1H-1-benzazepine 
• 137978-31-5 9-chloro-1-[4-[(2-methylbenzoyl)amino]benzoyl]-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine 
• 247237-61-2 9-chloro-1-(4-nitrobenzoyl)-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine 
• 137983-89-2 1-(4-aminobenzoyl)-9-chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine 
• 247237-52-1 9-chloro-5-oxo-2,3,4,5-tetrahydro-1-p-toluenesulfonyl-1H-1-benzazepine 

Relevant articles and documents

7-Chloro-5-hydroxy-1-[2-methyl-4-(2-methylbenzoylamino)benzoyl]-2,3,4,5- tetrahydro-1H-1-benzazepine (OPC-41061): A potent, orally active nonpeptide arginine vasopressin V2 receptor antagonist

We previously reported a series of benzazepine derivatives as orally active nonpeptide arginine vasopressin (AVP) V2 receptor antagonists. After the lead structure OPC-31260 was structurally evaluated and optimized, the introduction of the 7-Cl moiety on the benzazepine and 2-CH3 on the aminobenzoyl moiety enhanced its oral activity. The new AVP-V2 selective antagonist OPC-41061 was determined to be a potent and orally active agent. Copyright (C) 1999 Elsevier Science Ltd.