247237-56-5 Usage
General Description
9-chloro-1,2,3,4-tetrahydro-1-benzazepin-5-one, also known as Clozapine, is a psychoactive medication used to treat schizophrenia. It acts as an antagonist at dopamine and serotonin receptors in the brain, helping to reduce symptoms of psychosis and agitation. Clozapine has also been found to be effective in treating treatment-resistant schizophrenia and reducing the risk of suicide in patients with schizophrenia. However, it is associated with potentially serious side effects, including agranulocytosis, myocarditis, and seizures, and requires regular monitoring of white blood cell counts. Despite its side effects, Clozapine remains an important option for patients with schizophrenia who do not respond to other antipsychotic medications.
Check Digit Verification of cas no
The CAS Registry Mumber 247237-56-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,7,2,3 and 7 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 247237-56:
(8*2)+(7*4)+(6*7)+(5*2)+(4*3)+(3*7)+(2*5)+(1*6)=145
145 % 10 = 5
So 247237-56-5 is a valid CAS Registry Number.
247237-56-5Relevant articles and documents
Halogenated method of aromatic compound
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Paragraph 0062-0065, (2021/11/10)
The invention belongs to the field of organic synthesis, and particularly relates to synthesis of aromatic halogens, in particular to arylamine. The invention discloses a synthesis method of a corresponding ortho-halogenated product from aromatic compounds such as carbazole and phenol. The method comprises the following steps: adding a metal sulfonate salt catalyst, aromatic amine, carbazole, phenol and other hydrogen - heteroatom-containing aromatic compound reaction substrates, a halogenation reagent and a reaction solvent at a specific reaction temperature. After the drying agent is dried, the yield of the reaction product and the nuclear magnetic characterization determining structure are determined by column chromatography. The reaction product yield is determined by gas chromatography. By adopting the method, under the cheap metal salt catalyst, a plurality of ortho-substituted brominated and chloro products can be obtained with moderate to excellent yield.
