247569-42-2

Basic information

• Product Name: 4-Chloro-3-methoxybenzenemethanamine
• Synonyms: 4-chloro-3-methoxybenzenemethanamine;(4-chloro-3-methoxyphenyl)methanamine;(4-Chloro-3-methoxyphenyl)
• CAS NO: 247569-42-2
• Molecular Formula: C₈H₁₀ClNO
• Molecular Weight: 171.62
• Mol File: 247569-42-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 263.1 °C at 760 mmHg
• Flash Point: 112.9 °C
• Appearance: /
• Density: 1.18 g/cm³
• Vapor Pressure: 0.0105mmHg at 25°C
• Refractive Index: 1.549
• Storage Temp.: 2-8°C
• PKA: 8.83±0.10(Predicted)
• CAS DataBase Reference: 4-Chloro-3-methoxybenzenemethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-3-methoxybenzenemethanamine(247569-42-2)
• EPA Substance Registry System: 4-Chloro-3-methoxybenzenemethanamine(247569-42-2)

Safety Data

• Hazardous Substances Data: 247569-42-2(Hazardous Substances Data)

Usage

General Description

The chemical 4-Chloro-3-methoxybenzenemethanamine, also known as N-(4-chloro-3-methoxyphenyl)methanamine, is an organic compound with the molecular formula C8H10ClNO. It is a derivative of aniline and is commonly used as an intermediate in the synthesis of various pharmaceuticals and agricultural chemicals. 4-Chloro-3-methoxybenzenemethanamine is a white to light yellow solid and is mostly utilized in research and development settings to create new compounds for various applications. It is important to handle this chemical with caution as it can pose health risks if not properly managed.

InChI:InChI=1/C8H10ClNO/c1-11-8-4-6(5-10)2-3-7(8)9/h2-4H,5,10H2,1H3

Upstream product

• 169045-07-2 2-{[4-chloro-3-(methyloxy)phenyl]methyl}-1H-isoindole-1,3(2H)-dione 
• 247569-87-5 N-(2-chloro-5-methoxybenzyl)phthalimide 
• 3031-86-5 4-chloro-3-ethoxytoluene 
• 3771-13-9 2-(bromomethyl)-1-chloro-4-methoxybenzene 
• 615-74-7 2-chloro-5-methylphenol 
• 3446-90-0 4-(methylthio)benzyl alcohol 
• 874-89-5 4-Cyanobenzyl alcohol 
• 38185-19-2 4-(methylthio)benzyl bromide 
• 54788-17-9 2-chloro-4-methoxybenzyl bromide 
• 80866-88-2 (3-methoxy-4-nitrophenyl)methanol 
• 98544-66-2 4-bromomethyl-2,6-dichloro-anisole 
• 73909-16-7 2-chloro-5-methylanisole 
• 67341-33-7 2,6-dichloro-4-methylanisole 
• 89-60-1 1-chloro-4-methyl-2-nitro-benzene 

Downstream Products

• 247569-43-3 N-(4-chloro-3-methoxybenzyl)-2-fluoro-5-nitrobenzamide 
• 247567-34-6 N-Benzyl-2-[2-hydroxy-1-(hydroxymethyl)ethylamino]-5-nitrobenzamide 
• 247570-14-5 5-bromo-N-(4-chloro-3-methoxybenzyl)-2-fluorobenzamide 
• 247568-34-9 2-fluoro-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247569-57-9 N-(4-Chloro-3-methoxybenzyl)-2-fluoro-5-methanesulfonylbenzamide 
• 945995-37-9 1-(4-chloro-3-methoxybenzyl)-4-hydroxy-6-methylpyridin-2(1H)-one 
• 943816-63-5 5-(aminomethyl)-2-chlorophenol 
• 1466515-55-8 C₁₃H₁₈ClNO₃ 
• 247570-15-6 N-(4-chloro-3-methoxybenzyl)-2-fluoro-5-vinylbenzamide 
• 247570-16-7 5-acetyl-2-fluoro-N-(4-chloro-3-methoxybenzyl)benzamide 
• 247567-01-7 2-(tert-Butoxyamino)-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247568-30-5 (R)-5-Acetyl-N-(4-chloro-3-methoxybenzyl)-2-(2-hydroxy-1-methylethylamino)benzamide 
• 247566-86-5 (R)-2-(2-Hydroxy-1-methylethylamino)-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247566-87-6 5-Nitro-N-(1,3-benzodioxol-5-ylmethyl)-2-(2-thiazolylamino)benzamide 

Relevant articles and documents

SUBSTITUTED 2,4 DIAMINO-QUINOLINE AS NEW MEDICAMENT FOR FIBROSIS, AUTOPHAGY AND CATHEPSINS B (CTSB), L (CTSL) AND D (CTSD) RELATED DISEASES

The present invention relates to novel 2-primary amino-4-secondary amino-quinoline derivatives, their manufacture, pharmaceutical compositions comprising them and their use as medicaments. The active compounds of the present invention can be useful as a medicament in the treatment and/or the decreasing and/or the prevention of fibrosis and/or fibrosis related diseases, or for use as a medicament in the treatment and/or the decreasing and/or the prevention of the autophagy and/or autophagy related diseases and for the inhibition of the autophagy flux, or for use in the inhibition of cathepsins B (CTSB), L (CTSL) and/or D (CTSD) and/or cathepsins B (CTSB), L (CTSL) and/or D (CTSD) related diseases; with the proviso that said compounds are not to be used for the treatment of any forms of cancers.

Anthranilic acid derivatives as inhibitors of the cGMP-phosphodiesterase

Compounds of formula (I) STR1where R 1 is hydrogen; R 2 is nitro, cyano or halo(lower)alkyl; R 3 is phenyl substituted with one or more substituents selected from halogen, cyano and lower alkoxy; A is a lower alkylene group; R 4 is a group CR 6 R 7 R 8 wherein R 6 and R 7 form, together with the carbon atom to which they are attached a cycloalkyl group optionally substituted with hydroxy, lower alkoxy or a lower alkanoylamino; and R 8 is hydrogen; its prodrug and a salt thereof.