24765-56-8 Usage
Description
2-Ethyl-2-phenyl-1,3-propanediol is an organic compound with the molecular formula C11H16O2. It is a chiral molecule with a unique structure that features an ethyl group and a phenyl group attached to a 1,3-propanediol backbone. 2-ETHYL-2-PHENYL-1,3-PROPANEDIOL is known for its potential applications in the synthesis of various organic compounds and pharmaceuticals.
Uses
Used in Pharmaceutical Industry:
2-Ethyl-2-phenyl-1,3-propanediol is used as a key intermediate in the synthesis of pharmaceuticals, particularly those targeting the central nervous system. Its unique structure allows for the development of novel drugs with improved efficacy and selectivity.
Used in Organic Synthesis:
2-Ethyl-2-phenyl-1,3-propanediol is used as a versatile building block in organic synthesis, enabling the preparation of a wide range of organic compounds with diverse applications. Its ability to form all-carbon quaternary stereocenters makes it particularly valuable in the synthesis of complex organic molecules.
Used in Copper-Catalyzed Desymmetrization:
2-Ethyl-2-phenyl-1,3-propanediol is used in the preparation of all-carbon quaternary stereocenter compounds via copper-catalyzed desymmetrization of disubstituted propanediols with benzoyl chloride. This reaction provides a highly efficient and selective method for the synthesis of enantioenriched quaternary carbon centers, which are important structural motifs in many biologically active compounds and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 24765-56-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,7,6 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 24765-56:
(7*2)+(6*4)+(5*7)+(4*6)+(3*5)+(2*5)+(1*6)=128
128 % 10 = 8
So 24765-56-8 is a valid CAS Registry Number.
24765-56-8Relevant articles and documents
Aerobic oxidative desymmetrization of meso-diols with bifunctional amidoiridium catalysts bearing chiral N-sulfonyldiamine ligands
Moritani, Junki,Hasegawa, Yasuharu,Kayaki, Yoshihito,Ikariya, Takao
supporting information, p. 1188 - 1191 (2014/02/14)
Asymmetric aerobic oxidation of a range of meso- and prochiral diols with chiral bifunctional Ir catalysts is described. A high level of chiral discrimination ability of Cpa? -Ir complexes derived from (S,S)-1,2-diphenylethylenediamine was successfully demonstrated by desymmetrization of secondary benzylic diols such as cis-indan-1,3-diol and cis-1,4-diphenylbutane-1,4-diol, providing the corresponding (R)-hydroxyl ketones with excellent chemo- and enantioselectivities. Enantiotopic group discrimination in oxidation of symmetrical primary 1,4- and 1,5-diols gave rise to chiral lactones with moderate ees under similar aerobic conditions.
