24771-25-3

Basic information

• Product Name: DIMETHYL CYANOCARBONIMIDATE
• Synonyms: cyano-carbonimidicacidimethylester;cyano-dimidocarbonicacidimethylester;cyano-imidocarbonicacidimethylester;sk&f107533;DIMETHYL CYANOCARBONIMIDATE;DIMETHYL-N-CYANOIMIDOCARBONATE;CARBONIMIDIC ACID, CYANO-, DIMETHYL ESTER;dimethyl cyanoimidocarbonate
• CAS NO: 24771-25-3
• Molecular Formula: C₄H₆N₂O₂
• Molecular Weight: 114.1
• EINECS: 246-454-5
• Mol File: 24771-25-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 112.5°Cat760mmHg
• Flash Point: 21.8°C
• Appearance: /
• Density: 1.04g/cm³
• Vapor Pressure: 21.7mmHg at 25°C
• Refractive Index: 1.431
• Solubility: DMSO; Methanol; Water
• CAS DataBase Reference: DIMETHYL CYANOCARBONIMIDATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL CYANOCARBONIMIDATE(24771-25-3)
• EPA Substance Registry System: DIMETHYL CYANOCARBONIMIDATE(24771-25-3)

Safety Data

• Hazardous Substances Data: 24771-25-3(Hazardous Substances Data)

Usage

Description

DIMETHYL CYANOCARBONIMIDATE, also known as Dimethyl (N-Cyanoimido)carbonate, is an organic compound that serves as an intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its ability to react with other molecules, making it a versatile building block in the development of new drugs.

Uses

Used in Pharmaceutical Synthesis:
DIMETHYL CYANOCARBONIMIDATE is used as an intermediate in the synthesis of C988063, an impurity of Cimetidine (C441650). Cimetidine is a competitive histamine H2-receptor antagonist that inhibits gastric acid secretion and reduces pepsin output, making it useful in the treatment of conditions such as peptic ulcers and gastroesophageal reflux disease.
In the pharmaceutical industry, DIMETHYL CYANOCARBONIMIDATE plays a crucial role in the development of new drugs and the improvement of existing ones. Its reactivity and versatility make it a valuable compound for researchers and chemists working on drug synthesis and development.

InChI:InChI=1/C4H6N2O2/c1-7-4(8-2)6-3-5/h1-2H3

Upstream product

• 67-56-1 methanol 
• 10191-60-3 dimethyl N-cyanodithioiminocarbonate 
• 420-04-2 CYANAMID 
• 1850-14-2 tetramethoxymethane 
• 6263-27-0 Imidokohlensaeure-dimethylester 

Downstream Products

• 26364-65-8 2-(N-cyanoimino)thiazolidine 
• 31857-31-5 N¹,N²-dimethylcyanoguanidine 
• 795310-08-6 2-methoxy-6-amino-5,8-diaza-7,9-dicarbapurine 
• 26364-65-8 2-cyanoimino-1,3-thiazolidine 
• 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine 
• 82020-90-4 2-amino-4-isopropyl-6-methoxy-s-triazine 
• 26364-65-8 2-(cyanoimino)-thiazolidine 
• 146374-56-3 ethyl-(2-cyanoimino-5,6-dichloro-1,2,3,4-tetrahydroquinazolin-3-yl) acetate 

Relevant articles and documents

O-ethyl-S-n-propyl-(3-ethyl-2-cyano-imine-1-imidazole) process for synthesis of phosphate esters

The invention relates to a synthetic process of O-ethyl-S-n-proply-(3-ethyl-2-cyano imine-1-imidazole) phosphate. The process comprises the following steps of: 1) synthesis of O-ethyl-S-n-proply-S-propyl phosphoryl chloride; 2) synthesis of 1-ethyl-2-(N-cyano imine) imidazole; and 3) synthesis of O-ethyl-S-n-proply-(3-ethyl-2-cyano imine-1-imidazole) phosphate. The process provided by the invention has the beneficial effects that the reaction step and time are shortened, the yield is improved from 50% to over 70%, and the total yield is improved; according to the process, potassium carbonate replaces flammable and combustible sodium hydride, so that the reaction condition is more mild and the production process is safer; based on dipropyl dithio and phosphorus trichloride as initial raw materials, S-n-proply phosphoryl dichloride is synthesized and reacted with ethanol to obtain O-ethyl-S-n-propyl-phosphoryl chloride; the line is short and the raw material is easy to get with less wastewater, and the method is suitable for industrialization.

FUNGICIDAL TRICYCLIC 1,2,4-TRIAZOLES

Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, (I) wherein W is O, S(O)?n#191, NR5 or a direct bond; n is 0, 1 or 2; Q is O, S or NR6; G together with the two carbon atoms to which it is attached forms a 5 or 6-membered ring; and R1, R2, R3, R4, R5, and R6 are as defined in the Summary of the Invention. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.

METHOD FOR PRODUCING DIMETHYL CYANIMIDOCARBONATE

The invention relates to a novel method for producing dimethyl cyanimidocarbonate (DCC, 3,3-dimethoxy-2-azaprop-2-ene nitrile) from sodium cyanide, methanol, chlorine gas and cyanamide.