24771-26-4

Basic information

• Product Name: 2-cyano-1,1,3,3-tetramethylguanidine
• CAS NO: 24771-26-4
• Molecular Formula: C₆H₁₂N₄
• Molecular Weight: 140.1863
• Mol File: 24771-26-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 177.4°C at 760 mmHg
• Flash Point: 61.1°C
• Density: 0.94g/cm³
• Vapor Pressure: 1.04mmHg at 25°C
• Refractive Index: 1.481
• CAS DataBase Reference: 2-cyano-1,1,3,3-tetramethylguanidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyano-1,1,3,3-tetramethylguanidine(24771-26-4)
• EPA Substance Registry System: 2-cyano-1,1,3,3-tetramethylguanidine(24771-26-4)

Safety Data

• Hazardous Substances Data: 24771-26-4(Hazardous Substances Data)

Upstream product

• 506-68-3 bromocyane 
• 80-70-6 N,N,N',N'-tetramethylguanidine 
• 51108-31-7 N-cyano-S,N¹,N¹-trimethylisothiourea 
• 124-40-3 dimethyl amine 
• 78-67-1 2,2'-azobis(isobutyronitrile) 
• 75-05-8 acetonitrile 
• 7677-24-9 trimethylsilyl cyanide 

Relevant articles and documents

Electrochemical strategies for: N -cyanation of secondary amines and α C -cyanation of tertiary amines under transition metal-free conditions

Transition metal-free electrochemical approaches for the N-cyanation of secondary amines and the α C-cyanation of tertiary amines have been well established, with products being obtained in moderate to good yields and with good functional group tolerance under ambient conditions. The synthetic application of the protocols has been highlighted through scale-up experiments in a galvanostatic mode. Preliminary mechanistic investigation has confirmed that TBAB played a critical role in N-cyanation transformation and has indicated that the transformation might proceed via a free radical process. This journal is

Radical N-cyanation of sulfoximine through acetonitrile C-CN cleavage

A new strategy for the N-cyanation of sulfoximine via radical process has been developed, leading to the desired products in moderate to excellent yields with good functional group tolerance. This procedure provided an alternative pathway to C-CN bond act

APPLICATION OF PHOTOELECTRON SPECTROSCOPY TO BIOLOGICALLY ACTIVE MOLECULES AND THEIR CONSTITUENT PARTS. VII. N-CYANOAZOMETHINES

A series of N-cyanoazomethines 1-12 has been synthesized, and their electronic properties studied by He(I) photoelectron (PE) spectroscopy using the composite molecule approach.This allows partial assignment of the ionization energies in the PE spectrum of cimetidine 16, a known H2-receptor antagonist.Determination of differential UV spectra of the model compounds 7 and 13 revealed that no intramolecular charge transfer (CT) interaction exists between the two "ends" of the cimetidine molecule, i.e. between the ?-electron rich imidazole ring and the relatively ?-electron deficient cyanoguanidine moiety.