24785-42-0

Basic information

• Product Name: Benzene, 1-(2,2-dimethylpropyl)-2-methyl-
• CAS NO: 24785-42-0
• Molecular Formula: C12H18
• Molecular Weight: 162.275
• Mol File: 24785-42-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(2,2-dimethylpropyl)-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(2,2-dimethylpropyl)-2-methyl-(24785-42-0)
• EPA Substance Registry System: Benzene, 1-(2,2-dimethylpropyl)-2-methyl-(24785-42-0)

Safety Data

• Hazardous Substances Data: 24785-42-0(Hazardous Substances Data)

Upstream product

• 3282-30-2 pivaloyl chloride 
• 932-31-0 ortho-tolylmagnesium bromide 
• 15501-33-4 neopentyl iodide 
• 33872-80-9 o-tolyl magnesium chloride 
• 507-20-0 tertiary butyl chloride 
• 552-45-4 1-chloromethyl-2-methylbenzene 
• 2041-37-4 2,2-dimethyl-1-(o-tolyl)propan-1-one 

Downstream Products

• 33148-54-8 2-pivaloylbenzoic acid 
• 51351-79-2 2-(2,2-Dimethylpropyl)benzoic acid 

Relevant articles and documents

Nickel-Mediated Cross-Coupling of Unactivated Neopentyl Iodides with Organozincs

(dppf)NiCl2 catalyzes the cross-coupling of unactivated primary neopentyl iodides with diorganozinc reagents.The zinc nucleophiles are formed by the treatment of ZnCl2*dioxane with 2 mol equiv of a Grignard reagent in an etheral solvent.The cross-coupling works optimally for diorganozincs formed from aryl chlorides or CH3MgCl.Use of aryl bromides can cause reduction and/or reductive dimerization of the electrophile.The analogous reaction with (CH3)2CuMgCl in either the presence or the absence of Group 10 metal catalysts failed to afford reasonable yields of cross-coupled products.The diorganozinc methodology overcomes many of the side reactions observed with the (dppf)NiCl2-mediated cross-coupling of Grignard reagents.