24900-69-4

Basic information

• Product Name: 4-[(4-FLUOROPHENYL)SULFANYL]ANILINE
• Synonyms: 4-[(4-FLUOROPHENYL)SULFANYL]ANILINE;4-(4-FLUOROPHENYLTHIO)ANILINE;4-AMINO-4'-FLUORODIPHENYL THIOETHER;4-[(4-fluorophenyl)sulfanyl]phenylamine;4-(4-Fluorophenylthio)aniline97%
• CAS NO: 24900-69-4
• Molecular Formula: C₁₂H₁₀FNS
• Molecular Weight: 219.28
• Mol File: 24900-69-4.mol
• Article Data: 7

Chemical Properties

• Melting Point: 60-62°C
• Boiling Point: 390.9°Cat760mmHg
• Flash Point: 190.2°C
• Appearance: /
• Density: 1.27g/cm³
• Vapor Pressure: 2.56E-06mmHg at 25°C
• Refractive Index: 1.653
• CAS DataBase Reference: 4-[(4-FLUOROPHENYL)SULFANYL]ANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(4-FLUOROPHENYL)SULFANYL]ANILINE(24900-69-4)
• EPA Substance Registry System: 4-[(4-FLUOROPHENYL)SULFANYL]ANILINE(24900-69-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 24900-69-4(Hazardous Substances Data)

Usage

General Description

4-[(4-Fluorophenyl)sulfanyl]aniline is a chemical compound with the molecular formula C12H10FNS. It is a white to light brown solid that is soluble in organic solvents. This chemical is commonly used as a reagent in the synthesis of pharmaceutical drugs and other organic compounds. It has a variety of applications in the pharmaceutical, agricultural, and chemical industries due to its ability to act as a building block for more complex molecules. It is important to handle this compound with care as it can be hazardous if not properly managed.

InChI:InChI=1/C12H10FNS/c13-9-1-5-11(6-2-9)15-12-7-3-10(14)4-8-12/h1-8H,14H2

Upstream product

• 2438-85-9 4-fluorophenyl 4′-nitrophenyl sulfide 
• 371-42-6 4-Fluorothiophenol 
• 100-00-5 4-chlorobenzonitrile 
• 405-31-2 bis(4-fluorophenyl)disulfide 
• 62-53-3 aniline 
• 2266-41-3 4-fluorobenzenesulfonylhydrazide 

Downstream Products

• 62676-79-3 C,C,C-Trifluoro-N-[4-(4-fluoro-phenylsulfanyl)-phenyl]-methanesulfonamide 
• 90309-32-3 N-[4-[(4-Fluorophenyl)thio]phenyl]acetamide 
• 1155798-47-2 1-(2,6-diisopropylphenyl)-3-[4-(4-fluorophenylsulfanyl)phenyl]-urea 
• 1421708-18-0 benzyl 5-(4-fluorophenyl)sulfanylspiro[indoline-3,4'-piperidine]-1'-carboxylate 
• 1421708-19-1 benzyl 1-(2-chloropyridine-4-carbonyl)-5-(4-fluorophenyl)sulfanylspiro[indoline-3,4'-piperidine]-1'-carboxylate 
• 1421708-20-4 benzyl 1-(2-chloro-6-methyl-pyridine-4-carbonyl)-5-(4-fluorophenyl)sulfanylspiro[indoline-3,4'-piperidine]-1'-carboxylate 
• 1421708-21-5 benzyl 5-(4-fluorophenyl)sulfanyl-1-(2-methylpyridine-4-carbonyl)spiro[indoline-3,4'-piperidine]-1'-carboxylate 
• 1421707-07-4 (2-chloro-4-pyridyl)-[1'-[(E)-cinnamyl]-5-(4-fluorophenyl)sulfanylspiro[indoline-3,4'-piperidine]-1-yl]methanone 
• 1421707-26-7 (2-chloro-6-methyl-4-pyridyl)-[1'-[(E)-cinnamyl]-5-(4-fluorophenyl)sulfanylspiro[indoline-3,4'-piperidine]-1-yl]methanone 
• 1421707-06-3 [1'-[(E)-cinnamyl]-5-(4-fluorophenyl)sulfanylspiro[indoline-3,4'-piperidine]-1-yl]-(2-methyl-4-pyridyl)methanone 

Relevant articles and documents

Iodine/DMSO-Promoted Selective Direct Arylthiation of Anilines with Thiols under Metal-Free Conditions

An iodine-promoted divergent thiolation of unprotected anilines with thiols for the synthesis of sulfide anilines has been described. The combinational use of I2 and DMSO played an important role to realize this kind of transformation without the aid of a

Flavin/I2 catalyzed aerobic oxidative C–H sulfenylation of anilines

A flavin/I2 catalyzed aerobic oxidative C–H sulfenylation of anilines with thiols under mild reaction conditions is presented for the first time. This metal-free reaction provides an atom-economic pathway to prepare various aryl sulfides with outstanding functional group compatibility. Moreover, it consumes molecular oxygen as the only terminal oxidant and produces environmentally-friendly H2O as the only byproduct.

NOVEL SPIROINDOLINE COMPOUNDS

This invention relates to novel spiroindoline compounds of formula (I) that are generally useful as medicaments, more specifically as medicaments for animals. The medicament can preferably be used for the treatment of helminth infections and the treatment of parasitosis, such as caused by helminth infections. This invention also relates to uses of the compounds to make medicaments and treatments comprising the administration of the compounds to animals in need of the treatments. This invention also relates to the preparation of said compounds. Moreover this invention relates to pharmaceutical compositions and kits comprising the compounds.