25014-15-7

Basic information

• Product Name: POLY(2-VINYLPYRIDINE)
• Synonyms: RALU(R)PLATE LEV 170;POLY(2-VINYLPYRIDINE) CROSS-LINKED;POLY(2-VINYLPYRIDINE), LINEAR;POLY(2-VINYLPYRIDINE);POLY(2-VINYLPYRIDINE) 115'000;POLY(2-VINYLPYRIDINE) 12'000;POLY(2-VINYLPYRIDINE) 135'000;POLY(2-VINYLPYRIDINE) 21'000
• CAS NO: 25014-15-7
• Molecular Formula: C21H21N3X2
• Molecular Weight: 315.41
• EINECS: 202-852-0
• Product Categories: POLB - POLYMaterials Science;Polymer Molecular Weight Standards;Reference/Calibration Standards;Alphabetic;P;Poly(2-vinylpyridine);Organic Soluble Polymers;POLB - POLYPolymer Standards
• Mol File: 25014-15-7.mol
• Article Data: 73

Chemical Properties

• Boiling Point: 160.3°Cat760mmHg
• Flash Point: 46.7°C
• Appearance: /
• Density: 0.968g/cm³
• CAS DataBase Reference: POLY(2-VINYLPYRIDINE)(CAS DataBase Reference)
• NIST Chemistry Reference: POLY(2-VINYLPYRIDINE)(25014-15-7)
• EPA Substance Registry System: POLY(2-VINYLPYRIDINE)(25014-15-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 25014-15-7(Hazardous Substances Data)

Usage

Description

POLY(2-VINYLPYRIDINE) is a vinyl polymer composed of repeating -CH2-CRunits, where R is a 2-pyridyl group. It is a versatile and functional polymer with a wide range of applications due to its unique chemical and physical properties.

Uses

Used in Heterobifunctional Applications:
POLY(2-VINYLPYRIDINE) is used as a heterobifunctional polymer for monitoring PEGulation reactions. It is labeled with a fluorescein isothiocyanate group and a terminal amine reactive NHS group, which allows for efficient tracking and analysis of the PEGylation process.
Used in Chemical Synthesis Industry:
POLY(2-VINYLPYRIDINE) is used as a key component in the synthesis of various chemical compounds. Its unique structure and functional groups enable it to act as a versatile building block for the development of new materials and molecules with specific properties and applications.
Used in Pharmaceutical Industry:
POLY(2-VINYLPYRIDINE) is used as a starting material for the development of novel drug delivery systems. Its chemical and physical properties make it suitable for the design and synthesis of targeted drug carriers, which can improve the efficacy and bioavailability of therapeutic agents.
Used in Research and Development:
POLY(2-VINYLPYRIDINE) is used as a research tool in various scientific fields, including polymer science, materials science, and biochemistry. Its unique properties and functional groups make it an ideal candidate for studying the behavior of polymers and their interactions with other molecules and materials.
Used in Environmental Applications:
POLY(2-VINYLPYRIDINE) can be used in environmental applications, such as water treatment and pollution control. Its ability to form complexes with various contaminants and pollutants makes it a promising candidate for the development of new technologies and processes to address environmental challenges.

InChI:InChI=1/C7H7N/c1-2-7-5-3-4-6-8-7/h2-6H,1H2

Upstream product

• 109-06-8 α-picoline 
• 50-00-0 formaldehyd 
• 100-71-0 2-Ethylpyridine 
• 103-74-2 2-(2-Hydroxyethyl)pyridine 
• 110-86-1 pyridine 
• 67-56-1 methanol 
• 64-17-5 ethanol 
• 109-04-6 2-bromo-pyridine 
• 754-05-2 ethenyltrimethylsilane 
• 5029-67-4 2-iodopyridine 
• 931-19-1 2-methylpyridine N-oxide 
• 4833-24-3 2-ethylpyridine 1-oxide 
• 593-60-2 Vinyl bromide 
• 81745-83-7 pyridin-2-ylzinc(ll) bromide 

Downstream Products

• 6311-90-6 2-[2-(pyrrolidin-1-yl)ethyl]pyridine 
• 6973-67-7 2-(pyridin-2-yl)-N-(thiophen-2-ylmethyl)ethanamine 
• 6312-14-7 2-[2-(2,5-dimethyl-pyrrol-1-yl)-ethyl]-pyridine 
• 6304-22-9 2-(2-acetamidoethyl)pyridine 
• 4903-95-1 cis-ethyl 2-(pyridin-2-yl)cyclopropanecarboxylate 
• 4903-95-1 trans-ethyl 2-(pyridin-2-yl)cyclopropanecarboxylate 
• 55496-57-6 propyl-(2-[2]pyridyl-ethyl)-amine 
• 17624-26-9 2-(2-(pyridin-2-yl)ethyl)isoindoline-1,3-dione 
• 6312-33-0 diisobutyl-(2-pyridin-2-yl-ethyl)-amine 
• 30456-58-7 2-(2-methyl-cyclohex-3-enyl)-pyridine 
• 35549-47-4 2-(2-Cyanoethyl)pyridine 
• 59020-97-2 S-2-(2-pyridyl)ethyl thioacetate 
• 136704-09-1 2,2-diphenyl-4-[2]pyridyl-butyronitrile 
• 110145-50-1 8-phenyl-3-(2-pyridin-2-yl-ethyl)-benzo[e][1,3]oxazine-2,4-dione 

Relevant articles and documents

Continuous Flow Process for the Synthesis of Betahistine via Aza-Michael-Type Reaction in Water

A continuous flow process for the preparation of betahistine with a 90% isolated yield has been reported. 2-Vinylpyridine and saturated methylamine hydrochloride aqueous solution were used as starting materials to achieve excellent results in the silicon carbide flow reactor, which can tolerate the corrosion of chloride ions at high temperature (170 °C) and pressure (25 bar). In the continuous flow process, the product can be obtained in 2.4 min with excellent conversion (>99%) and product selectivity (94%). The throughput can reach 1.06 kg h-1, and the purity of the final product was greater than 99.9% by distillation, which were in accordance with the needs of production. This new process using environmentally friendly water as the solvent is energy-efficient, time- and cost-economic, and offers a 50% reduction in process mass intensity compared to the batch process.

KO-t-Bu Catalyzed Thiolation of β-(Hetero)arylethyl Ethers via MeOH Elimination/hydrothiolation

Herein, we describe a KO-t-Bu catalyzed thiolation of β-(hetero)arylethyl ethers through MeOH elimination to form (hetero)arylalkenes followed by anti-Markovnikov hydrothiolation to afford linear thioethers. The system works well with a variety of β-(hetero)arylethyl ethers, including electron-deficient, electron-neutral, electron-rich, and branched substrates and a range of aliphatic and aromatic thiols.

Piperazine-promoted gold-catalyzed hydrogenation: The influence of capping ligands

Gold nanoparticles (NPs) combined with Lewis bases, such as piperazine, were found to perform selective hydrogenation reactions via the heterolytic cleavage of H2. Since gold nanoparticles can be prepared by many different methodologies and using different capping ligands, in this study, we investigated the influence of capping ligands adsorbed on gold surfaces on the formation of the gold-ligand interface. Citrate (Citr), poly(vinyl alcohol) (PVA), polyvinylpyrrolidone (PVP), and oleylamine (Oley)-stabilized Au NPs were not activated by piperazine for the hydrogenation of alkynes, but the catalytic activity was greatly enhanced after removing the capping ligands from the gold surface by calcination at 400 °C and the subsequent adsorption of piperazine. Therefore, the capping ligand can limit the catalytic activity if not carefully removed, demonstrating the need of a cleaner surface for a ligand-metal cooperative effect in the activation of H2 for selective semihydrogenation of various alkynes under mild reaction conditions.