250369-59-6Relevant articles and documents
Synthesis of Fused Tetrahydrofuran-γ-lactone Motifs via One-Pot Ring Expansion of Cyclopropane Rings
Kom, Charles,Brady, Thomas,Kim, Sun Hee,Theodorakis, Emmanuel A.
, p. 1951 - 1966 (2004)
An efficient method for constructing fused tetrahydrofuran-γ-lactone scaffolds, such as 8, is presented. Key to this strategy is an acid-catalyzed ring expansion of cyclopropyl precursor 6 that proceeds in the presence of MeSO3H in acetone and produces th
Synthetic studies on norrisolide: Enantioselective synthesis of the norrisane side chain
Kim, Charles,Hoang, Richard,Theodorakis, Emmanuel A.
, p. 1295 - 1297 (2008/02/09)
Norrisolide (1) belongs to a family of marine diterpenes that are characterized by the assembly of a bicyclic core with a unique and highly oxygenated side chain (norrisane side chain). As a prelude to the synthesis of 1, we present herein a short, effici