25039-88-7

Basic information

• Product Name: 2-cyclohexyl-4,5-dimethyl-1,3-thiazole
• Synonyms: 2-cyclohexyl-4,5-dimethyl-1,3-thiazole
• CAS NO: 25039-88-7
• Molecular Weight: 195.329
• Mol File: 25039-88-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-cyclohexyl-4,5-dimethyl-1,3-thiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyclohexyl-4,5-dimethyl-1,3-thiazole(25039-88-7)
• EPA Substance Registry System: 2-cyclohexyl-4,5-dimethyl-1,3-thiazole(25039-88-7)

Safety Data

• Hazardous Substances Data: 25039-88-7(Hazardous Substances Data)

Upstream product

• 3581-91-7 4,5-Dimethylthiazole 
• 2043-61-0 cyclohexanecarbaldehyde 
• 626-62-0 Cyclohexyl iodide 
• 1122-56-1 cyclohexylcarboxamide 
• 814-75-5 3-bromo-butanone 

Relevant articles and documents

Dioxygen-Mediated Decarbonylative C-H Alkylation of Heteroaromatic Bases with Aldehydes

An operationally simple and economical method for the direct alkylation of heteroaromatic bases employing readily available aldehydes as alkyl radical precursors and molecular oxygen as a reagent is presented. This simple transformation demonstrates a broad substrate scope with respect to aldehydes and nitrogen heterocycles, enabling the introduction of several medicinally important yet challenging alkyl moieties, such as ethyl, isopropyl, tert-butyl, and cyclohexyl to the different classes of heterocyclic bases in good to excellent yields. A simple method for the direct alkylation of heteroaromatic bases with aldehydes as inexpensive alkyl radical precursors and molecular oxygen as a reagent is presented. This transformation demonstrates a broad substrate scope with respect to aldehydes and nitrogen heterocycles, enabling the introduction of various alkyl moieties to heterocyclic bases (>40 examples) in good to excellent yields.