250591-26-5

Basic information

• Product Name: Acetic acid (S)-1-phenyl-2-pyridin-2-yl-ethyl ester
• Synonyms: Acetic acid (S)-1-phenyl-2-pyridin-2-yl-ethyl ester
• CAS NO: 250591-26-5
• Molecular Weight: 241.29
• Mol File: 250591-26-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid (S)-1-phenyl-2-pyridin-2-yl-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid (S)-1-phenyl-2-pyridin-2-yl-ethyl ester(250591-26-5)
• EPA Substance Registry System: Acetic acid (S)-1-phenyl-2-pyridin-2-yl-ethyl ester(250591-26-5)

Safety Data

• Hazardous Substances Data: 250591-26-5(Hazardous Substances Data)

Upstream product

• 2294-74-8 1-phenyl-2-pyridin-2-yl-ethanol 
• 1620-53-7 1-phenyl-2-pyridin-2-ylethanone 
• 250591-25-4 acetic acid 1-phenyl-2-pyridin-2-yl-ethyl ester 

Downstream Products

• 112653-26-6 (1S)-1-Phenyl-2<(2R)-2-piperidyl>ethanol 
• 1415-36-7 (-)-norsedamine 
• 497-88-1 (-)-sedamine 
• 2294-74-8 (S)-1-phenyl-2-(pyridin-2-yl)ethan-1-ol 

Relevant articles and documents

A concise synthesis of homochiral sedamines and related alkaloids. A new reductive application of Jacobsen's catalyst

Two methods for the generation of both enantiomers of sedamine [1- methyl-2-(2-phenyl-2-hydroxy-1-ethyl)piperidine] in high optical purity have been elaborated. The first utilises the lipase-mediated kinetic resolution of racemic acetates and the second involves the NaBH4 mediated reduction of ketones catalysed by Jacobsen's catalyst. Some related applications of these reactions are also disclosed.