25063-69-8

Basic information

• Product Name: 5 - [[(6 - Methoxypyridin - 3 - yl)aMino]Methylidene] - 2,2 - diMethyl - 1,3 - dioxane - 4,6 - dione
• Synonyms: 5 - [[(6 - Methoxypyridin - 3 - yl)aMino]Methylidene] - 2,2 - diMethyl - 1,3 - dioxane - 4,6 - dione;5-((6-methoxypyridin-3-ylamino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione
• CAS NO: 25063-69-8
• Molecular Formula: C₁₃H₁₄N₂O₅
• Molecular Weight: 278.26066
• EINECS: -0
• Mol File: 25063-69-8.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 5 - [[(6 - Methoxypyridin - 3 - yl)aMino]Methylidene] - 2,2 - diMethyl - 1,3 - dioxane - 4,6 - dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5 - [[(6 - Methoxypyridin - 3 - yl)aMino]Methylidene] - 2,2 - diMethyl - 1,3 - dioxane - 4,6 - dione(25063-69-8)
• EPA Substance Registry System: 5 - [[(6 - Methoxypyridin - 3 - yl)aMino]Methylidene] - 2,2 - diMethyl - 1,3 - dioxane - 4,6 - dione(25063-69-8)

Safety Data

• Hazardous Substances Data: 25063-69-8(Hazardous Substances Data)

Usage

General Description

5 - [[(6 - Methoxypyridin - 3 - yl)aMino]Methylidene] - 2,2 - diMethyl - 1,3 - dioxane - 4,6 - dione is a chemical compound with the molecular formula C13H16N2O5. It is a pyridine derivative with a dioxane ring structure. 5 - [[(6 - Methoxypyridin - 3 - yl)aMino]Methylidene] - 2,2 - diMethyl - 1,3 - dioxane - 4,6 - dione has potential biological activity due to its amino and methylidene functional groups. It may be used in pharmaceutical research as a building block for the synthesis of new compounds with potential therapeutic applications, or as a reference standard in analytical chemistry. However, further research is needed to fully understand its properties and potential uses.

Upstream product

• 6628-77-9 6-methoxy-pyridin-3-ylamine 
• 2033-24-1 cycl-isopropylidene malonate 
• 122-51-0 orthoformic acid triethyl ester 
• 15568-85-1 5-methoxymethylene-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 23443-25-6 6-methoxy-1,5-naphthyridin-4-ol 
• 23443-25-6 6-methoxy-1,5-naphthyridin-4(1H)-one 
• 1431984-59-6 C₂₅H₃₀N₆O₂ 
• 1431984-60-9 C₃₀H₄₁N₇O₂ 
• 1431984-75-6 C₂₃H₂₄F₂N₆ 
• 1431984-74-5 C₂₃H₂₄F₂N₆ 
• 1431984-61-0 C₂₆H₂₈N₈O₄S 
• 1431984-62-1 C₂₃H₂₁N₅O₂ 
• 1431984-65-4 2,8-dichloro-7-(1-methyl-1H-pyrazol-4-yl)-1,5-naphthyridine 
• 1431984-85-8 C₂₅H₂₈N₆O₂ 
• 1431984-63-2 C₂₂H₂₂BrN₅O₂ 
• 1431984-64-3 C₂₄H₂₃N₇O₂ 
• 1431985-36-2 C₂₀H₁₉N₅O₂ 
• 1431985-37-3 C₂₈H₃₇N₅O₃Si 

Relevant articles and documents

SIX-MEMBERED AND SIX-MEMBERED HETEROCYCLIC COMPOUND AND USES THEREOF SERVING AS PROTEIN RECEPTOR KINASE INHIBITOR

Provided are a preparation and applications of a six-membered fused with six-membered heterocyclic compound, specifically, provided in the present invention is a compound as represented by formula I as follows, where the definitions of the groups are as described in the description. The compound has TRK kinase inhibiting activity and can serve as a pharmaceutical composition for treating TRK dysfunction-related diseases.

Process for Manufacturing a Naphthyridine Derivative

The invention relates to a process and synthetic intermediates that can be used for manufacturing the compound of formula (1-6) which is a synthetic intermediate useful in the preparation of antibiotic compounds.

Aurora Kinase Modulators and Method of Use

The present invention relates to chemical compounds having a general formula I wherein A1-8, D′, L1, L2, R1, R6-8 and n are defined herein, and synthetic intermediates, which are capable of modulating various protein kinase receptor enzymes and, thereby, influencing various disease states and conditions related to the activities of such kinases. For example, the compounds are capable of modulating Aurora kinase thereby influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. The invention also includes pharmaceutical compositions, including the compounds, and methods of treating disease states related to the activity of Aurora kinase.