250723-56-9

Basic information

• Product Name: 2-acetylamino-3-(4-cyano-2-fluoro-phenyl)-propionic acid
• CAS NO: 250723-56-9
• Molecular Weight: 250.229
• Mol File: 250723-56-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-acetylamino-3-(4-cyano-2-fluoro-phenyl)-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-acetylamino-3-(4-cyano-2-fluoro-phenyl)-propionic acid(250723-56-9)
• EPA Substance Registry System: 2-acetylamino-3-(4-cyano-2-fluoro-phenyl)-propionic acid(250723-56-9)

Safety Data

• Hazardous Substances Data: 250723-56-9(Hazardous Substances Data)

Upstream product

• 170572-49-3 2-fluoro-4-cyanotoluene 
• 51436-99-8 2-fluoro-4-bromotoluene 
• 105942-09-4 4-(bromomethyl)-3-fluorobenzonitrile 
• 1068-90-2 2-acetylaminomalonic acid diethyl ester 

Downstream Products

• 250723-65-0 3-(4-cyano-2-fluoro-phenyl)-N-cyclopentyl-N-methyl-2-(5,6,7,8-tetrahydro-naphthalene-2-sulfonylamino)-propionamide 
• 250723-66-1 3-(4-cyano-2-fluoro-phenyl)-N-cyclopentyl-2-(6-methoxy-naphthalene-2-sulfonylamino)-N-methyl-propionamide 
• 250723-63-8 3-(4-cyano-2-fluoro-phenyl)-N-cyclopentyl-N-methyl-2-(4-propyl-benzenesulfonylamino)-propionamide 
• 250723-61-6 3-(4-cyano-2-fluoro-phenyl)-N-cyclopentyl-N-methyl-2-(naphthalene-2-sulfonylamino)-propionamide 
• 250723-59-2 [2-(4-cyano-2-fluoro-phenyl)-1-(cyclopentyl-methyl-carbamoyl)-ethyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

Fluorobenzamidrazone thrombin inhibitors: Influence of fluorine on enhancing oral absorption

LB30057 (1) is a selective and efficacious oral thrombin inhibitor. Fluorine-substitution on the phenylene ring of the benzamidrazone portion in both compound 1 and its derivatives gave, in many cases, enhanced oral absorption in rats while maintaining the intrinsic potency and selectivity. Compound 2 demonstrated a 3-fold increase in absorption.