251092-74-7

Basic information

• Product Name: 4-phenyl-2H-3-benzo[b]pyranylcarboxaldehyde
• Synonyms: 4-phenyl-2H-3-benzo[b]pyranylcarboxaldehyde
• CAS NO: 251092-74-7
• Molecular Weight: 236.27
• Mol File: 251092-74-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-phenyl-2H-3-benzo[b]pyranylcarboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-phenyl-2H-3-benzo[b]pyranylcarboxaldehyde(251092-74-7)
• EPA Substance Registry System: 4-phenyl-2H-3-benzo[b]pyranylcarboxaldehyde(251092-74-7)

Safety Data

• Hazardous Substances Data: 251092-74-7(Hazardous Substances Data)

Upstream product

• 108-95-2 phenol 
• 491-37-2 2,3-dihydro-4H-1-benzopyran-4-one 
• 14063-82-2 4-chloro-2H-chromene-3-carboxaldehyde 
• 98-80-6 phenylboronic acid 
• 51870-64-5 4-phenyl-2H-benzo[b]pyran 
• 68-12-2 N,N-dimethyl-formamide 

Relevant articles and documents

Synthesis and antimicrobial activity of 2-(4-phenyl-2h-chromen-3-yl)-1h-benzo[d]imidazole

A new series of 4-phenyl-2H-chromene-3-benzimidazoles (8a-o) were synthesized by the condensation of 4-phenyl-2H-chromene-3- carbaldehyde with o-phenylene diamines. The products were purified through column chromatography and structures of these compounds were characterized by IR, 1H & 13C NMR and mass spectral data. All the final compounds were screened for their antimicrobial activity and their efficacy were matched with ciprofloxacin. Five compounds (8b, 8d, 8i, 8l and 8o) were found to be most effective compounds of this series and with activities improved than ciprofloxacin under the tested conditions.

CHROMENE DERIVATIVES AS PHOSHOINOSITIDE 3-KINASES INHIBITORS

The invention relates to compounds inhibiting phosphoinositide 3-kinases (PI3K), to pharmaceutical compositions comprising them and therapeutic use thereof in the treatment of disorders associated with PI3K enzymes.