251293-28-4 Usage
Description
Urotensin II (Human) is a neuropeptide that plays a significant role in various physiological processes, including the regulation of cardiovascular function, renal function, and central nervous system activity. It is derived from the human body and has been a subject of interest for its potential therapeutic applications.
Uses
Used in Pharmaceutical Research:
Urotensin II (Human) is used as an agonist and antagonist in calcium mobilization assays, which are essential for understanding the molecular mechanisms underlying various physiological and pathological processes. These assays help researchers study the effects of different compounds on cellular signaling pathways and their potential applications in drug development.
Used in Cardiovascular Research:
Urotensin II (Human) is used as a test compound for studying the impact of dihydropyridine calcium antagonists, such as amlodipine, on human internal mammary arteries. This research is crucial for understanding the clinical implications of these drugs in treating cardiovascular diseases and developing new therapeutic strategies.
Biochem/physiol Actions
Human urotensin II is a vasoactive neuropeptide that belongs to CRF family and stimulates arterial smooth muscle contraction, actin stress fiber formation and proliferation via small GTPase RhoA and there downstream effector Rho-kinase activation.The product is also a selective and potent vasoconstrictor agent as well as an agonist for the orphan receptor GPR14.
Check Digit Verification of cas no
The CAS Registry Mumber 251293-28-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,1,2,9 and 3 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 251293-28:
(8*2)+(7*5)+(6*1)+(5*2)+(4*9)+(3*3)+(2*2)+(1*8)=124
124 % 10 = 4
So 251293-28-4 is a valid CAS Registry Number.
