251320-34-0

Basic information

• Product Name: methyl [N^α-(tert-butoxycarbonyl)-Nε-(2-chlorobenzylcarbonyl)-L-lysyl]-L-serinate
• Synonyms: methyl [N^α-(tert-butoxycarbonyl)-Nε-(2-chlorobenzylcarbonyl)-L-lysyl]-L-serinate
• CAS NO: 251320-34-0
• Molecular Weight: 515.991
• Mol File: 251320-34-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl [N^α-(tert-butoxycarbonyl)-Nε-(2-chlorobenzylcarbonyl)-L-lysyl]-L-serinate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl [N^α-(tert-butoxycarbonyl)-Nε-(2-chlorobenzylcarbonyl)-L-lysyl]-L-serinate(251320-34-0)
• EPA Substance Registry System: methyl [N^α-(tert-butoxycarbonyl)-Nε-(2-chlorobenzylcarbonyl)-L-lysyl]-L-serinate(251320-34-0)

Safety Data

• Hazardous Substances Data: 251320-34-0(Hazardous Substances Data)

Upstream product

• 5680-80-8 methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride 
• 54613-99-9 Boc-(S)-Lys(2-Cl-Z)-OH 

Downstream Products

• 251320-35-1 methyl [N^α-(tert-butoxycarbonyl)-N^ε-(2-chlorobenzyloxycarbonyl)-L-lysyl]-O-(tert-butyl-dimethylsilyl)-L-serinate 
• 251320-29-3 {(S)-5-[(S)-2-{(S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-hexanoylamino)-propionylamino]-3-methyl-butyrylamino}-6-(2-chloro-benzyloxycarbonylamino)-hexanoylamino]-6-oxo-hexyl}-carbamic acid 2-chloro-benzyl ester 
• 251320-40-8 [N^α-(tert-butyloxycarbonyl)-N^ε-(2-chlorobenzyloxycarbonyl)-L-lysyl]-N^ε-(2-chlorobenzyloxycarbonyl)-L-lysinal 
• 251320-43-1 [N^α-(tert-butyloxycarbonyl)-N^ε-(2-chlorobenzyloxycarbonyl)-L-lysyl]-N^ε-(2-chlorobenzyloxycarbonyl)-L,D-lysinal 
• 251320-36-2 methyl (2S)-N-[2-(tert-butoxycarbonylamino)-6-(2-chlorobenzyloxycarbonylamino)-hexanethiocarboxyl]-L-serinate 
• 251320-37-3 methyl (1'S,4S)-2-[1'-(tert-butoxycarbonylamino)-5'-(2-chlorobenzyloxycarbonylamino)pentyl]-2-thiazoline-4-carboxylate 
• 251320-38-4 methyl (1'S,4S)-2-[1-(tert-butoxycarbonylamino)-5'-(2-chlorobenzyloxycarbonylamino)pentyl]-3-methyl-2-thiazolidine-4-carboxylate 
• 251320-39-5 (1'S,4S)-2-[1'-(tert-butoxycarbonylamino)-5'-(2-chlorobenzyloxycarbonylamino)pentyl]-3-methyl-2-thiazolidine-4-carboxylic acid 
• 916138-32-4 C₅₆H₆₄Cl₃N₉O₁₅ 
• 916138-31-3 C₅₇H₆₆Cl₃N₉O₁₅ 
• 1004055-04-2 C₅₁H₅₄Cl₃N₉O₁₂ 
• 916138-30-2 2-[1-({2-[1-tert-butoxycarbonylamino-5-(2-chloro-benzyloxycarbonylamino)-pentyl]-oxazole-4-carbonyl}-amino)-5-(2-chloro-benzyloxycarbonylamino)-pentyl]-oxazole-4-carboxylic acid methyl ester 
• 916138-26-6 2-[1-tert-butoxycarbonylamino-5-(2-chlorobenzyloxycarbonylamino)pentyl]oxazole-4-carboxylic acid 
• 916138-24-4 2-[1-tert-butoxycarbonylamino-5-(2-chlorobenzyloxycarbonylamino)pentyl]oxazole-4-carboxylic acid methyl ester 

Relevant articles and documents

Solid phase synthesis of a Ψ[CH2NH] pseudopeptide by ligation of a peptidyl aldehyde with a resin-bound amino peptide

Solid phase synthesis of Ψ[CH2NH] pseudopeptide 3 was accomplished by reductive amination of peptidyl aldehyde 1 with resin bound amino peptide 2. No epimerization took place during the aldehyde preparation or the reductive amination step. This convergent strategy should facilitate the synthesis of analogues of the neuropeptide PACAP.