25144-04-1

Basic information

• Product Name: TRANS-2-METHYLCYCLOPENTANOL
• Synonyms: trans-2-Methylcyclopentanol,97%;TRANS-2-METHYLCYCLOPENTANOL;(E)-2-methylcyclopentanol;trans-2-methylcyclopentan-1-ol;Trans-2-Methylcyclopentanol(WX641033)
• CAS NO: 25144-04-1
• Molecular Formula: C₆H₁₂O
• Molecular Weight: 100.16
• EINECS: 246-652-1
• Product Categories: Oxygen Compounds;Alcohols;C2 to C6
• Mol File: 25144-04-1.mol
• Article Data: 25

Chemical Properties

• Melting Point: 17.63°C (estimate)
• Boiling Point: 150-151 °C740 mm Hg(lit.)
• Flash Point: 117 °F
• Appearance: /
• Density: 0.92 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.45(lit.)
• Storage Temp.: Flammables area
• PKA: 15.33±0.40(Predicted)
• CAS DataBase Reference: TRANS-2-METHYLCYCLOPENTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: TRANS-2-METHYLCYCLOPENTANOL(25144-04-1)
• EPA Substance Registry System: TRANS-2-METHYLCYCLOPENTANOL(25144-04-1)

Safety Data

• Statements: 10
• Safety Statements: 16
• RIDADR: UN 1987 3/PG 3
• WGK Germany: 3
• HazardClass: 3.2
• PackingGroup: III
• Hazardous Substances Data: 25144-04-1(Hazardous Substances Data)

Usage

Description

TRANS-2-METHYLCYCLOPENTANOL, also known as trans-2-methylcyclopentanol, is an organic compound that is one of the constituents of Gynandropsis gynandra oil. It is a colorless liquid with a distinctive odor and is characterized by its molecular structure, which includes a cyclopentanol ring with a methyl group at the 2-position.

Uses

Used in Fragrance Industry:
TRANS-2-METHYLCYCLOPENTANOL is used as a fragrance ingredient for its distinctive and pleasant odor. It is commonly utilized in the creation of perfumes, colognes, and other scented products to provide a unique and appealing fragrance.
Used in Flavor Industry:
TRANS-2-METHYLCYCLOPENTANOL is used as a flavoring agent for its ability to impart a specific taste to various food and beverage products. It can be found in the formulation of flavors for candies, beverages, and other consumable items, enhancing their overall taste profile.
Used in Pharmaceutical Industry:
TRANS-2-METHYLCYCLOPENTANOL is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure allows it to be a valuable building block for the development of new drugs and medications.
Used in Chemical Industry:
TRANS-2-METHYLCYCLOPENTANOL is used as a chemical intermediate for the production of various chemicals and materials. Its versatile structure makes it a useful component in the synthesis of a wide range of compounds, including solvents, resins, and other specialty chemicals.
Used in Research and Development:
TRANS-2-METHYLCYCLOPENTANOL is used as a research compound for studying its properties and potential applications in various fields. Scientists and researchers utilize this compound to explore its chemical reactivity, stability, and other characteristics, which can lead to the discovery of new applications and uses.

InChI:InChI=1/C6H12O/c1-5-3-2-4-6(5)7/h5-7H,2-4H2,1H3/t5-,6-/m1/s1

Upstream product

• 1120-72-5 2-Methylcyclopentanone 
• 693-89-0 1-methylcyclopent-1-ene 
• 117391-09-0 1-methyl-2-(1-oxa-4-mercaptobutyl)cyclopentane 
• 135879-52-6 Mercapto-acetic acid 2-methyl-cyclopentyl ester 
• 121416-57-7 2-(3-Bromo-propyl)-3-methyl-oxirane 
• 40911-83-9 tris(trans-2-methylcyclopentyl)borane 
• 63452-95-9 1,4-bis(bromomagnesio)pentane 
• 109-94-4 formic acid ethyl ester 
• 2396-80-7 methyl 5-hexenoate 
• 89155-67-9 tert-Butyl-dimethyl-(2-methyl-cyclopentyloxy)-silane 
• 109-99-9 tetrahydrofuran 
• 285-67-6 Cyclopentene oxide 
• 75-24-1 trimethylaluminum 
• 851541-78-1 6-iodo-3-(methoxymethoxy)-1-hexene 

Downstream Products

• 93427-73-7 (+/-)-3,5-dinitro-benzoic acid-(trans-2-methyl-cyclopentyl ester) 
• 100373-09-9 (+/-)-4-nitro-benzoic acid-(trans-2-methyl-cyclopentyl ester) 
• 110434-51-0 cis-1-methyl-2-(phenylthio)cyclopentane 
• 36367-81-4 trans-2-methylcylopentyl p-bromobenzenesulfonate 
• 693-89-0 1-methylcyclopent-1-ene 
• 85982-46-3 1-fluoro-1-methylcyclopentane 
• 66-25-1 hexanal 
• 1120-72-5 2-Methylcyclopentanone 

Relevant articles and documents

Synthesis of ω-chain-modified analogues of 7-oxaprostaglandins

-

Stereochemistry of the cyclization of alkoxy-substituted 5-hexenyllithiums: Effect of solvent and lithium iodide on diastereoselectivity

The stereochemistry of the cyclization of 4-methoxy-5-hexenyllithium, 4-(methoxymethoxy)-5-hexenyllithium, 4-tert-butoxy-5-hexenyllithium, and 3-methoxy-5-hexenyllithium, each of which was generated from the corresponding iodide by low-temperature lithium-iodine exchange, has been studied in a variety of solvent systems. The results of these studies demonstrate that the stereochemical outcome of the cyclizations of alkoxy-substituted 5-hexenyllithiums may be profoundly affected by the medium in which the ring closures are conducted. The etiology of these often dramatic solvent effects is attributed to the ability of certain lithiophilic ligands to competitively complex the lithium iodide salt that is present as a co-product from the exchange reaction used to prepare the organolithiums.

Lewis base-catalyzed addition of trialkylaluminum compounds to epoxides

A novel concept for catalytic epoxide alkylation has been developed. Lewis bases like phosphanes, arsanes, stibanes, and sulfides were found to catalyze the alkylation of symmetrical epoxides with trialkylaluminum compounds very effectively at a 5 mol % level. Cyclic as well as acyclic epoxides were readily alkylated in good yields. In reactions with terminal epoxides a significant enhancement of rate and/or regioselectivity was noted in the Lewis base-catalyzed process. Coordination of the Lewis base to the Lewis acidic aluminum reagent was proved by 27Al and 31p NMR spectroscopy and is proposed to form a more nucleophilic alkylating agent.

Electroreductive intramolecular cyclization of olefinic esters and its application to the synthesis of muscone

-