251451-30-6 Usage
Description
Zolmitriptan N-Oxide is a metabolite of Zolmitriptan, which is a medication primarily used to treat migraine headaches. It is a white solid with specific chemical properties that make it a significant compound in the pharmaceutical industry. As a metabolite, Zolmitriptan N-Oxide is formed during the body's metabolism of Zolmitriptan, playing a role in the drug's overall effectiveness and safety profile.
Uses
Used in Pharmaceutical Industry:
Zolmitriptan N-Oxide is used as a metabolite for Zolmitriptan, which is an important application in the pharmaceutical industry. It contributes to the overall efficacy and safety of the medication used to treat migraines. The presence of this metabolite in the body can help researchers understand the drug's metabolism and potentially improve its formulation or administration methods.
Used in Quality Control and Standardization:
Zolmitriptan N-Oxide, being a metabolite of Zolmitriptan, is also used for quality control and standardization purposes in the manufacturing process of Zolmitriptan. It serves as a reference compound (USP Related Compound E) to ensure the purity, potency, and consistency of the final drug product, which is crucial for its effectiveness and safety in patients.
Used in Research and Development:
In the field of research and development, Zolmitriptan N-Oxide is used as a subject of study to better understand the metabolic pathways and pharmacokinetics of Zolmitriptan. This knowledge can lead to the development of new drugs with improved efficacy, reduced side effects, or alternative routes of administration. Additionally, studying the metabolite can provide insights into the drug's interactions with other medications or substances, which is essential for optimizing patient care and minimizing drug interactions.
Check Digit Verification of cas no
The CAS Registry Mumber 251451-30-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,1,4,5 and 1 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 251451-30:
(8*2)+(7*5)+(6*1)+(5*4)+(4*5)+(3*1)+(2*3)+(1*0)=106
106 % 10 = 6
So 251451-30-6 is a valid CAS Registry Number.
InChI:InChI=1/C16H21N3O3/c1-19(2,21)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-22-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)
251451-30-6Relevant articles and documents
Tungstale-catalyzed oxidation of triptans with hydrogen peroxide: A novel method for the synthesis of N,N- Dimethyltryptamine N-oxides
Ray, Puma Chandra,Mittapelli, Vasantha,Chauhan, Yogendra Kumar,Konudula, Babu Rao,Tyagi, Om Dutt
experimental part, p. 134 - 136 (2009/12/01)
A straight forward oxidation method of triptans have been described for the synthesis of N,N-dimethyl-Z-[5-[substituted-lH-indole-3-yl]ethanamine-N-oxides using sodium tungstate and 30% aqueous hydrogen peroxide solution in the presence of methanesulphonic acid. The significance of the process is its simplicity and efficiency in isolating the triptan N-oxide derivatives as free base and as malate salt.
