25195-85-1Relevant articles and documents
Total synthesis of formamicin
Durham, Timothy B.,Blanchard, Nicolas,Savall, Brad M.,Powell, Noel A.,Roush, William R.
, p. 9307 - 9317 (2007/10/03)
The enantioselective total synthesis of the cytotoxic plecomacrolide natural product formamicin (1) is described. Key aspects of this synthesis include the efficient transacetalation reactions of MOM ethers 28 and 38 to form the seven-membered formyl acet
Studies on the Total Synthesis of Formamicin: Synthesis of the C(1)-C(11) Fragment
Powell, Noel A.,Roush, William R.
, p. 453 - 456 (2007/10/03)
(Matrix Presented) An efficient and highly concise synthesis of 6, corresponding to the C(1)-C(11) fragment of formamicin (1), has been accomplished by a route utilizing a diastereoselective lactate aldol reaction to set the C(6) tertiary ether and the TE
Carbohydrates as chiral auxiliaries: Synthesis of 2-hydroxy-β-D-glucopyranosides
Charette,Marcoux,Cote
, p. 7215 - 7218 (2007/10/02)
A new 2-step, 1-pot procedure for the stereoselective glycosylation of allylic alcohols with 1,2-di-O-benzoyl-β-D-glucopyranosides to produce 2-hydroxy-β-D-glucopyranosides has been developed. The required precursor for the glycosylation was readily obtained from tri-O-benzyl-D-glucal in 2 steps (91% overall).