25256-97-7 Usage
Description
(6a,11b,16a)-6,9-Difluoro-11-hydroxy-16-methylandrosta-1,4-diene-3,17-dione is a synthetic steroid compound derived from the androstane skeleton. It features a unique structure with two fluorine atoms at the 6 and 9 positions, a hydroxyl group at the 11 position, and a methyl group at the 16 position. (6a,11b,16a)-6,9-Difluoro-11-hydroxy-16-methylandrosta-1,4-diene-3,17-dione exhibits anti-inflammatory properties and is a derivative of the glucocorticoid class of steroids.
Uses
Used in Pharmaceutical Industry:
(6a,11b,16a)-6,9-Difluoro-11-hydroxy-16-methylandrosta-1,4-diene-3,17-dione is used as a glucocorticoid for its anti-inflammatory activities. It is particularly effective in treating various inflammatory conditions, such as allergies, asthma, and autoimmune disorders, due to its ability to modulate immune responses and reduce inflammation.
Used in Anti-inflammatory Applications:
As a derivative of Flumethasone, a glucocorticoid with potent anti-inflammatory properties, (6a,11b,16a)-6,9-Difluoro-11-hydroxy-16-methylandrosta-1,4-diene-3,17-dione is employed for its ability to alleviate inflammation and suppress the immune system. This makes it a valuable compound for managing inflammatory diseases and conditions that require immunosuppression.
Check Digit Verification of cas no
The CAS Registry Mumber 25256-97-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,2,5 and 6 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 25256-97:
(7*2)+(6*5)+(5*2)+(4*5)+(3*6)+(2*9)+(1*7)=117
117 % 10 = 7
So 25256-97-7 is a valid CAS Registry Number.
InChI:InChI=1/C20H24F2O3/c1-10-6-12-13-8-15(21)14-7-11(23)4-5-19(14,3)20(13,22)16(24)9-18(12,2)17(10)25/h4-5,7,10,12-13,15-16,24H,6,8-9H2,1-3H3/t10-,12+,13+,15+,16+,18+,19+,20+/m1/s1
25256-97-7Relevant articles and documents
Noncommunicating photoreaction paths in some pregna-1,4-diene-3,20-diones
Ricci, Andrea,Fasani, Elisa,Mella, Mariella,Albini, Angelo
, p. 8086 - 8093 (2001)
The photochemistry of three pregna-1,4-diene-3,20-diones bearing a hydroxy or alkoxy group at C17 (4-6) has been examined. Irradiation at 254 or 366 nm, where absorption by the cross-conjugated ketone moiety in ring A is predominant or exclusive, causes the 'lumiketone' rearrangement of this chromophore in low to medium quantum yield (Φr 0.05 to 0.31). On the contrary, irradiation at 310 nm, where the isolated ketone at C20 absorbs a large portion of light causes Norrish-I fragmentation of that chromophore with a higher Φr (0.11-0.83). This leads to end-products arising from the conversion of the C17 alkyl radical, in a way depending on the structure and the medium (reduction by hydrogen donating solvent, addition of oxygen when present). No intramolecular T-T energy transfer between the separated chromophores occurs. The 'lumiketone' rearrangement occurs independently from the irradiation wavelength (Φr 0.06-0.18) with the strictly related androsta-1,4-dien-3-one 8 lacking the C20 ketone function.
