25279-67-8 Usage
Description
(13α,17α)-7α-Acetoxy-21,23-epoxy-4,4,8-trimethyl-24-nor-5α-chola-1,14,20,22-tetren-3-one is a tetracyclic triterpenoid derived from 4,4,8-trimethylandrosta-1,14-diene. It is characterized by the presence of an oxo group at position 3, an acetoxy group at position 7, and a furan-3-yl group at position 17. (13α,17α)-7α-Acetoxy-21,23-epoxy-4,4,8-trimethyl-24-nor-5α-chola-1,14,20,22-tetren-3-one is isolated from the plant Azadirachta indica and has been found to exhibit antiplasmodial and antineoplastic activities.
Uses
Used in Pharmaceutical Industry:
(13α,17α)-7α-Acetoxy-21,23-epoxy-4,4,8-trimethyl-24-nor-5α-chola-1,14,20,22-tetren-3-one is used as a pharmaceutical agent for its antiplasmodial and antineoplastic properties. The compound is particularly effective against plasmodium parasites, which are responsible for malaria, and various types of cancer cells. Its ability to target and inhibit the growth of these harmful organisms makes it a promising candidate for the development of new treatments and therapies.
Used in Drug Delivery Systems:
Similar to gallotannin, (13α,17α)-7α-Acetoxy-21,23-epoxy-4,4,8-trimethyl-24-nor-5α-chola-1,14,20,22-tetren-3-one can also be incorporated into drug delivery systems to enhance its efficacy and bioavailability. By utilizing various organic and metallic nanoparticles as carriers, the compound can be more effectively delivered to target cells, improving its therapeutic outcomes and potentially reducing side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 25279-67-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,2,7 and 9 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 25279-67:
(7*2)+(6*5)+(5*2)+(4*7)+(3*9)+(2*6)+(1*7)=128
128 % 10 = 8
So 25279-67-8 is a valid CAS Registry Number.
InChI:InChI=1/C28H36O4/c1-17(29)32-24-15-22-25(2,3)23(30)10-13-27(22,5)21-9-12-26(4)19(18-11-14-31-16-18)7-8-20(26)28(21,24)6/h8,10-11,13-14,16,19,21-22,24H,7,9,12,15H2,1-6H3/t19-,21+,22-,24+,26-,27+,28?/m0/s1
25279-67-8Relevant articles and documents
LIMONOIDS FROM TRICHILIA HAVANENSIS
Arenas, Carlos,Rodriguez-Hahn, Lydia
, p. 2953 - 2956 (1990)
The limonoids of the seeds of Trichilia havanensis were studied in two ripening stages.From the unripened seeds azadirone, havanensin triacetate and three new limonoids were isolated.The mature seeds contained havanensin triacetate and its hydroxy lactone derivative.The structures of the new limonoids were deduced by spectroscopic and chemical means.
Tetranortriterpenoids and Related Compounds. Part 26. Tecleanin, a Possible Precursor of Limonin, and Other New Tetranortriterpenoids from Teclea grandifolia Engl. (Rutaceae)
Ayafor, J. Foyere,Sondengam, B. Lucas,Connolly, Josef D.,Rycroft, David S.,Okogun, Josef I.
, p. 1750 - 1753 (2007/10/02)
Tecleanin and 7-deacetylproceranone, two new tetranortriterpenoids from Teclea grandifolia Engl. (Rutaceae), have been assigned structures (2) and (4) respectively.Tecleanin has the same highly oxidised ring A as limonin but a carbocyclic ring D.A third new limonoid was indentified as 7-deacetylazadirone (13).
