25288-75-9

Basic information

• Product Name: (1E,4E)-1,5-Bis(4-nitrophenyl)penta-1,4-dien-3-one
• Synonyms: (1E,4E)-1,5-Bis(4-nitrophenyl)penta-1,4-dien-3-one;1,4-Pentadien-3-one, 1,5-bis(4-nitrophenyl)-
• CAS NO: 25288-75-9
• Molecular Formula: C₁₇H₁₂N₂O₅
• Molecular Weight: 324.28758
• Mol File: 25288-75-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (1E,4E)-1,5-Bis(4-nitrophenyl)penta-1,4-dien-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (1E,4E)-1,5-Bis(4-nitrophenyl)penta-1,4-dien-3-one(25288-75-9)
• EPA Substance Registry System: (1E,4E)-1,5-Bis(4-nitrophenyl)penta-1,4-dien-3-one(25288-75-9)

Safety Data

• Hazardous Substances Data: 25288-75-9(Hazardous Substances Data)

Usage

General Description

The chemical compound "(1E,4E)-1,5-Bis(4-nitrophenyl)penta-1,4-dien-3-one" is a yellow, crystalline solid that is composed of two 4-nitrophenyl groups attached to a penta-1,4-diene-3-one molecule. It is commonly used in organic synthesis and chemical research as a starting material for the preparation of various compounds, including pharmaceuticals and agrochemicals. The compound has been shown to possess significant anti-inflammatory and anticancer properties, making it a valuable tool for studying the biological activities of similar compounds. Additionally, its chemical structure makes it a useful intermediate for the synthesis of more complex organic molecules. However, it is important to handle this compound with caution, as it is classified as a hazardous substance and should be used in a well-ventilated area with proper personal protective equipment.

Upstream product

• 555-16-8 4-nitrobenzaldehdye 
• 67-64-1 acetone 
• 70307-28-7 (E)-4-(4-Nitro-phenyl)-1-(triphenyl-λ⁵-phosphanylidene)-but-3-en-2-one 

Downstream Products

• 3156-41-0 1-nitro-4-(2-nitrovinyl)benzene 
• 122228-67-5 bis (4-p-nitrophenyl-2-pyrazolin-3-yl) ketone 
• 115846-80-5 3-Methyl-7-(4-nitro-phenyl)-5-[(E)-2-(4-nitro-phenyl)-vinyl]-1-phenyl-1,6,7,8-tetrahydro-pyrazolo[3,4-b][1,4]diazepine 
• 1262238-68-5 C₂₀H₁₄N₄O₅ 
• 1309883-49-5 ethyl (2R,6R)-2,6-bis(4-nitrophenyl)-2',4-dioxospiro[cyclohexane-1,3'-indoline]-1'-carboxylate 
• 1383844-54-9 C₂₈H₂₇N₃O₆ 

Relevant articles and documents

Cu(OAc)2/TFA-promoted formal [3 + 3] cycloaddition/oxidation of enamines and enones for synthesis of multisubstituted aromatic amines

New strategies for the oxidative cycloaddition of enones with enamines are developed. These cycloaddition reactions directly afford substituted aromatic amines, which are important in organic chemistry, in moderate to good yield. Cu(OAc)2/TFA is shown to be essential to achieve high reaction efficiency.