253142-26-6

Basic information

• Product Name: 3-benzyl-2-methoxy-5-methyl-4-pyrimidinone
• Synonyms: 3-benzyl-2-methoxy-5-methyl-4-pyrimidinone
• CAS NO: 253142-26-6
• Molecular Weight: 230.266
• Mol File: 253142-26-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-benzyl-2-methoxy-5-methyl-4-pyrimidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-2-methoxy-5-methyl-4-pyrimidinone(253142-26-6)
• EPA Substance Registry System: 3-benzyl-2-methoxy-5-methyl-4-pyrimidinone(253142-26-6)

Safety Data

• Hazardous Substances Data: 253142-26-6(Hazardous Substances Data)

Upstream product

• 1024-41-5 benzyl tosylate 
• 25902-91-4 2-methoxy-5-methylpyrimidin-4(3H)-one 
• 100-39-0 benzyl bromide 

Downstream Products

• 21473-22-3 3-benzyl-5-methyl-2,4(1H)-pyrimidinedione 

Relevant articles and documents

HSAB driven chemoselectivity in alkylation of uracil derivatives. A high yielding preparation of 3-alkylated and unsymmetrically 1,3-dialkylated uracils

A qualitative hardness scale (N134) has been found for the conjugated bases of 2-methoxy-4(3H)-pyrimidinones 1-3 and applied to high yielding chemoselective N3 methylation, ethylation and benzylation reactions. Removal of the 2-methoxy group followed by a second alkylation affords unsymmetrically 1,3-disubstituted uracils.