253350-34-4Relevant articles and documents
Design and synthesis of a selective EP4-receptor agonist. Part 3: 16-phenyl-5-thiaPGE(1) and 9-beta-halo derivatives with improved stability.
Maruyama, Toru,Asada, Masaki,Shiraishi, Tai,Yoshida, Hideyuki,Maruyama, Takayuki,Ohuchida, Shuichi,Nakai, Hisao,Kondo, Kigen,Toda, Masaaki
, p. 1743 - 1759 (2007/10/03)
To identify a new selective EP4-agonist with improved chemical stability, further chemical modification of those reported previously was continued. We focused our attention on chemical modification of the alpha chain of 3,7-dithiaPGE(1) and selected 5-thi
3,7-dithiaprostanoic acid derivative
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, (2008/06/13)
A 3,7-dithiaprostanoic acid derivative of the formula (I) STR1 (wherein, R1 is OH, C16 alkyloxy, NR6 R7 (R6, R7 are H, C16 alkyl.); R2 is H, OH; R3 is single bond, C16 alkylene; R4 is (i) C18 alkyl substituted by C16 alkyloxy, halogen etc., (ii) phenyloxy