253434-23-0Relevant articles and documents
CHROMENOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS
-
Paragraph 0356, (2019/07/13)
The invention relates to inhibitors of PI5P4K inhibitors useful in the treatment of cancers, neurodegenerative diseases, inflammatory disorders, and metabolic diseases, having the Formula (I); where A1, A2, G, R1, R2, R3, R4, and W are described herein.
THIENO[2,3-C]PYRANS AS CFTR MODULATORS
-
Paragraph 00221, (2015/02/25)
The present invention discloses compounds according to Formula I: Wherein R is as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment cystic fibrosis by administering a compound of the invention.
An Expedient Synthesis of Cyclopropanone Cyanohydrins
Hartmann, Willy
, p. 272 - 274 (2007/10/02)
A practical and general synthesis of cyclopropanone cyanohydrins starting from readily available 1-hydroxycyclopropanecarboxylic acids is described.