253594-54-6Relevant articles and documents
COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
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Page/Page column 125, (2010/06/11)
This invention relates to compounds of the Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof.
MUSCARINIC ANTAGONISTS
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Page 21, (2010/02/06)
Amide derivatives of 1,4 di-substituted piperidine compounds of formula (I) or a pharmaceutically acceptable salt, ester or solvate thereof, wherein Q and Q are each -CH=, or one of Q and Q is -CH= and the other is -N=; X is -CH2- or (a); Y and Z are -C(R)=, or one of Y and Z is -C(R)= and the other is -N=; R is 1 to 3 substituents selected from H, halogen and alkoxy; R and R are 1 to 3 substituents selected from H, halogen, alkyl and alkoxy; and R and R are H or (C1-C6) alkyl are muscarinic antagonists usuful for treating cognitive disorders such as Alzheimer's disease. Pharmaceutical compositions and methods of preparation are also disclosed.
Concise formation of 4-benzyl piperidines and related derivatives using a Suzuki protocol
Vice,Bara,Bauer,Evans,Ford,Josien,McCombie,Miller,Nazareno,Palani,Tagat
, p. 2487 - 2492 (2007/10/03)
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