253771-21-0 Usage
Description
AR-C 102222 is a selective inhibitor of mitochondrial complex II, also known as succinate dehydrogenase, which plays a crucial role in cellular respiration and energy production. It has been found to have potential applications in various fields, particularly in the study and treatment of neurodegenerative diseases.
Uses
Used in Neurodegenerative Disease Research:
AR-C 102222 is used as a research tool for investigating the role of mitochondrial dysfunction in neurodegenerative diseases, such as Parkinson's disease. By inhibiting complex II, it helps to understand the underlying mechanisms and develop potential therapeutic strategies.
Used in Parkinson's Disease Diagnosis and Therapy Monitoring:
AR-C 102222 is used as an inhibitor in the method for the in vitro diagnosis and therapy monitoring of Parkinson's disease by measuring blood nitro-α-synuclein. This allows for the assessment of disease progression and the effectiveness of treatments, ultimately aiding in the development of personalized medicine approaches for patients with Parkinson's disease.
Check Digit Verification of cas no
The CAS Registry Mumber 253771-21-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,3,7,7 and 1 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 253771-21:
(8*2)+(7*5)+(6*3)+(5*7)+(4*7)+(3*1)+(2*2)+(1*1)=140
140 % 10 = 0
So 253771-21-0 is a valid CAS Registry Number.
253771-21-0Relevant articles and documents
Pharmaceutical combination comprising a COX-2 inhibitor and a iNOS inhibitor
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, (2008/06/13)
The invention relates to the co-administration of an inhibitor of induced nitric oxide synthase and an inhibitor of cyclooxygenase-2 for the treatment of inflammation and inflammatory disorders.
