25379-15-1Relevant articles and documents
Syntheses of 7H-pyrido- and 7H-pyrano[2,3,4-kl]acridin-2(3H)-ones from 9-chloroacridines
Gorelik,Titova,Gordievskaya
, p. 1664 - 1669 (2006)
A method for peri-annulation of the pyridine or pyran ring to acridine was developed and used to obtain 7H-pyrido-and 7H-pyrano[2,3,4-kl]acridin-2(3H)- ones. The peri-groups were formed by a reaction of 9-chloro-1-nitroacridine with a CH-acid (malononitri
Synthesis of ascididemine and an isomer
Alvarez, Mercedes,Feliu, Lidia,Ajana, Wadi,Joule, John A.,Fernandez-Puentes, Jose Luis
, p. 849 - 855 (2007/10/03)
Ascididemine (9H-quino[4,3,2-de][1,10]phenanthrolin-9-one) (1) and an isomer (9H-quino[4,3,2-de][1,7]phenanthrolin-9-one) (4) have been synthesized starting from 1,4-dimethoxyacridone (7). The acridone was converted into 1,4- dimethoxy-9-ethynylacridine (
Structure-trypanodical activity relationships
Bsiri,Johnson,Kayirere,Galy,Galy,Barbe,Osuna,Mesa-Valle,Castilla Calvente,Rodriguez-Cabezas
, p. 27 - 33 (2007/10/03)
A set of 9-thioalkylacridinones, has been prepared and investigated' in vitro' against T. cruzi. Structure-antiparasitic activity relationships are detailed with a view to identify the major structural parameters for the activity under consideration.