25395-11-3 Usage
Description
Triacetyl Aloe-emodin (Impurity A) is a chemical compound derived from Aloe-emodin, which is a naturally occurring anthraquinone present in various plants, including the aloe plant. It is characterized by its yellow solid appearance and is known for its potential applications in different industries due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
Triacetyl Aloe-emodin (Impurity A) is used as an active pharmaceutical ingredient for its potential therapeutic effects. It is recognized for its anti-inflammatory, antioxidant, and antimicrobial properties, which contribute to its use in the development of drugs for various health conditions.
Used in Cosmetic Industry:
In the cosmetic industry, Triacetyl Aloe-emodin (Impurity A) is used as an additive for its skin-friendly properties. It is valued for its ability to soothe and protect the skin, making it a suitable ingredient for skincare products aimed at addressing inflammation, oxidative stress, and microbial imbalances.
Used in Research and Development:
Triacetyl Aloe-emodin (Impurity A) is also utilized in research and development settings as a compound of interest for studying its chemical behavior, interactions with other molecules, and potential applications in various fields, including drug discovery and material science.
Check Digit Verification of cas no
The CAS Registry Mumber 25395-11-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,3,9 and 5 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 25395-11:
(7*2)+(6*5)+(5*3)+(4*9)+(3*5)+(2*1)+(1*1)=113
113 % 10 = 3
So 25395-11-3 is a valid CAS Registry Number.
InChI:InChI=1/C21H16O8/c1-10(22)27-9-13-7-15-19(17(8-13)29-12(3)24)21(26)18-14(20(15)25)5-4-6-16(18)28-11(2)23/h4-8H,9H2,1-3H3
25395-11-3Relevant articles and documents
Rizk et al.
, p. 2122,2124 (1972)
Synthesis, biological evaluation and molecular modeling of aloe-emodin derivatives as new acetylcholinesterase inhibitors
Shi, Da-Hua,Huang, Wei,Li, Chao,Wang, Ling-Ting,Wang, Shi-Fan
, p. 1064 - 1073 (2013/03/14)
A series of aloe-emodin derivatives were designed, synthesized and evaluated as acetylcholinesterase inhibitors. Most of the new prepared compounds showed remarkable acetylcholinesterase inhibitory activities. Among them, the compound 1-((4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yl) methyl) pyridin-1-ium chloride (C3) which has a pyridinium substituent possessed the best inhibitory activity of acetylcholinesterase (IC50 = 0.09 μM). The docking study performed with AUTODOCK demonstrated that C3 could interact with the catalytic active site (CAS) and the peripheral anionic site (PAS) of acetylcholinesterase.
