25413-69-8

Basic information

• Product Name: N-butyl-N-nitrosoaniline
• Synonyms: Benzenamine, N-butyl-N-nitroso-; N-Butyl-N-nitrosobenzenamine
• CAS NO: 25413-69-8
• Molecular Formula: C₁₀H₁₄N₂O
• Molecular Weight: 178.231
• Mol File: 25413-69-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 296.7°C at 760 mmHg
• Flash Point: 133.2°C
• Density: 1g/cm³
• Vapor Pressure: 0.00142mmHg at 25°C
• Refractive Index: 1.519
• CAS DataBase Reference: N-butyl-N-nitrosoaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-butyl-N-nitrosoaniline(25413-69-8)
• EPA Substance Registry System: N-butyl-N-nitrosoaniline(25413-69-8)

Safety Data

• Hazardous Substances Data: 25413-69-8(Hazardous Substances Data)

Upstream product

• 1126-78-9 N-(n-butyl)aniline 
• 3416-49-7 N-butyl-N-methylaniline 
• 62-53-3 aniline 

Downstream Products

• 61715-75-1 N-butyl-N-phenylhydrazine 
• 41657-74-3 N-butyl-4-nitroso-aniline 
• 74607-61-7 3-Butyl-2-(4-methoxy-phenyl)-3H-benzo[1,3,2]thiazaphosphole 2-sulfide 
• 1126-78-9 N-(n-butyl)aniline 
• 72342-55-3 (2-(butylamino)phenyl)(phenyl)methanone 
• 5589-61-7 2-(butylamino)benzonitrile 

Relevant articles and documents

Three-Component Couplings among Heteroarenes, Difluorocyclopropenes, and Water via C-H Activation

Three-component couplings have been realized for efficiently constructing various nitrogen-containing skeletons via C-H activation, where difluorocyclopropenes have been first identified as coupling partners. Many substrates including sp2 and sp3 C-H substrates were well tolerated, furnishing the corresponding products in good yields. Furthermore, a catalyst-dependent reaction was also developed, enabling divergent construction of two different frameworks. The application value of these reactions was demonstrated in gram-scale experiments with as little as 1 mol % catalyst.

N-Dealkylation-N-nitrosation of Tertiary Aromatic Amines by n-Butyl Nitrite

N,N-Dialkyl aromatic amines with a variety of ring substituents are N-dealkylated and N-nitrosated efficiently by n-butyl nitrite/ammonium chloride/water at reflux temperature.Ring nitrosation was never observed, but minor amounts of m- and p-nitro amines and/or nitrosamines were formed in some cases.Ring nitration is rather a reaction of the initial substrate than a process occurring on formed nitrosamines.The leaving propensities of the initial N-substituents to yield nitrosamines were in the order benzyl >> methyl >> alkyl.Key Words: Nitrosamines; N-Dealkylation; N-Nitrosation; C-Nitration; Alkyl nitrite.