25478-53-9

Basic information

• Product Name: 2-benzyl-5,6-dihydro-4H-1,3-thiazine
• CAS NO: 25478-53-9
• Molecular Formula: C₁₁H₁₃NS
• Molecular Weight: 191.2926
• Mol File: 25478-53-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 307.8°C at 760 mmHg
• Flash Point: 140°C
• Density: 1.11g/cm³
• Vapor Pressure: 0.00128mmHg at 25°C
• Refractive Index: 1.602
• CAS DataBase Reference: 2-benzyl-5,6-dihydro-4H-1,3-thiazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyl-5,6-dihydro-4H-1,3-thiazine(25478-53-9)
• EPA Substance Registry System: 2-benzyl-5,6-dihydro-4H-1,3-thiazine(25478-53-9)

Safety Data

• Hazardous Substances Data: 25478-53-9(Hazardous Substances Data)

Upstream product

• 109-70-6 1.3-chlorobromopropane 
• 645-54-5 2-phenylthioacetamide 
• 103-82-2 phenylacetic acid 
• 462-47-5 mercapto-3 propylamine 
• 124932-16-7 N-(3-hydroxypropyl)-2-phenylacetamide 
• 103-80-0 phenylacetyl chloride 

Downstream Products

• 1384256-37-4 (Z)-3-(2,2-dichlorobutanoyl)-2-benzylidene-1,3-thiazinane 
• 1384256-41-0 (Z)-3-(dichlorophenylacetyl)-2-(Z)-benzylidene-1,3-thiazinane 
• 1384256-66-9 1-(3-(6-oxo-7,8-diphenyl-3,4,6,8a-tetrahydro-2H-pyrrolo[2,1-b]-1,3-thiazin-8a-ylthio)propyl)-3,4-diphenyl-1H-pyrrole-2,5-dione 
• 1384256-65-8 1,1'-[3,3'-disulfanediylbis(propane-3,1-diyl)]bis(3,4-diphenyl-1H-pyrrole-2,5-dione) 
• 1384256-58-9 3-ethyl-1-{3-(7-ethyl-6-oxo-8-phenyl-3,4,6,8a-tetrahydro-2H-pyrrolo[2,1-b]-1,3-thiazin-8a-ylthio)propyl}-4-phenyl-1H-pyrrole-2,5-dione 
• 1384256-57-8 1,1'-[3,3'-disulfanediylbis(propane-3,1-diyl)]bis(3-ethyl-4-phenyl-1H-pyrrole-2,5-dione) 

Relevant articles and documents

Microwave-Assisted Synthesis of 2-Substituted 2-Thiazolines and 5,6-Dihydro-4 H -1,3-thiazines

An efficient and general method for the synthesis of 2-substituted thiazolines and 5,6-dihydro-4 H -1,3-thiazines is developed via microwave-assisted ring closure of ω-thioamidoalcohols promoted by ethyl polyphosphate (PPE). The cyclization reaction involves an S N 2-type mechanism and features the advantages of very short reaction times, high yields and a predictable stereochemical outcome. The acyclic precursors are prepared in high overall yields by an improved diacylation-thionation-saponification sequence from commercially available ω-amino alcohols. The whole process is metal-free and operationally simple.

Novel anthelmintic agents. V. Thiazoline and dihydrothiazine analogs of pyrantel.

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