25491-47-8

Basic information

• Product Name: ethyl 2-benzoyl-3-methylbutanoate
• Synonyms: ethyl 2-benzoyl-3-methylbutanoate;Benzenepropanoic acid, a-(1-methylethyl)-b-oxo-, ethyl ester
• CAS NO: 25491-47-8
• Molecular Formula: C₁₄H₁₈O₃
• Molecular Weight: 234.29092
• EINECS: -0
• Mol File: 25491-47-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 307.6°C at 760 mmHg
• Flash Point: 130.6°C
• Appearance: /
• Density: 1.044g/cm³
• Vapor Pressure: 0.000719mmHg at 25°C
• Refractive Index: 1.498
• CAS DataBase Reference: ethyl 2-benzoyl-3-methylbutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-benzoyl-3-methylbutanoate(25491-47-8)
• EPA Substance Registry System: ethyl 2-benzoyl-3-methylbutanoate(25491-47-8)

Safety Data

• Hazardous Substances Data: 25491-47-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H18O3/c1-4-17-14(16)12(10(2)3)13(15)11-8-6-5-7-9-11/h5-10,12H,4H2,1-3H3

Upstream product

• 108-64-5 Ethyl isovalerate 
• 93-89-0 benzoic acid ethyl ester 
• 75-30-9 2-iodo-propane 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 613-90-1 benzoyl cyanide 
• 63547-55-7 1-ethoxy-3-methyl-1-trimethylsiloxybut-1-ene 
• 75-26-3 isopropyl bromide 
• 92655-51-1 2-benzoyl-3-methyl-pentanoic acid ethyl ester 
• 65-85-0 benzoic acid 
• 98-88-4 benzoyl chloride 

Downstream Products

• 582-62-7 3-methyl-1-phenylbutan-1-one 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 92655-51-1 2-benzoyl-3-methyl-pentanoic acid ethyl ester 
• 857413-38-8 C₁₃H₁₅N₃O 
• 1628208-23-0 6-isopropyl-7-oxo-5-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile 

Relevant articles and documents

COMPOUND HAVING KDM5 INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF

The present invention provides KDM5 inhibitor. The compound disclosed herein represented by the general formula (Z): wherein all symbols have the same meanings as the definitions described in the specification; or a salt thereof is useful as a prophylactic and/or therapeutic agent for cancer, Huntington's disease, or Alzheimer's disease and the like.

Dynamic Kinetic Resolution of Alkenyl Cyanohydrins Derived from α,β-Unsaturated Aldehydes: Stereoselective Synthesis of E-Tetrasubstituted Olefins

A novel dynamic kinetic resolution (DKR) of tetrasubstituted alkenyl cyanohydrins prepared from the corresponding α,β-unsaturated aldehydes is described. The deprotonation of a geometrical mixture of tetrasubstituted alkenyl cyanohydrins with sodium diiso

Identification of potent, selective KDM5 inhibitors

This communication describes the identification and optimization of a series of pan-KDM5 inhibitors derived from compound 1, a hit initially identified against KDM4C. Compound 1 was optimized to afford compound 20, a 10?nM inhibitor of KDM5A. Compound 20