25546-50-3

Basic information

• Product Name: 2,3,4,5-TETRA-O-ACETYL-D-RIBONITRILE
• Synonyms: 2,3,4,5-TETRA-O-ACETYL-D-RIBONITRILE;2,3,4,5-Tetra-O-acetyl-D-ribononitrile;2-O,3-O,4-O,5-O-Tetraacetyl-D-ribononitrile;D-Ribononitrile, 2,3,4,5-tetraacetate;Nsc39092;Ribononitrile, 2,3,4,5-tetraacetate, D-
• CAS NO: 25546-50-3
• Molecular Formula: C₁₃H₁₇NO₈
• Molecular Weight: 315.276
• Mol File: 25546-50-3.mol
• Article Data: 14

Chemical Properties

• Melting Point: 72 °C
• Boiling Point: 435.7°Cat760mmHg
• Flash Point: 190.3°C
• Appearance: /
• Density: 1.253g/cm³
• CAS DataBase Reference: 2,3,4,5-TETRA-O-ACETYL-D-RIBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4,5-TETRA-O-ACETYL-D-RIBONITRILE(25546-50-3)
• EPA Substance Registry System: 2,3,4,5-TETRA-O-ACETYL-D-RIBONITRILE(25546-50-3)

Safety Data

• Hazardous Substances Data: 25546-50-3(Hazardous Substances Data)

Usage

General Description

2,3,4,5-Tetra-O-acetyl-D-ribonitrile is a chemical compound with the molecular formula C10H15NO7. It is a derivative of D-ribose, a common sugar found in the body, and has four acetyl groups attached to the hydroxyl groups of the ribonitrile. 2,3,4,5-TETRA-O-ACETYL-D-RIBONITRILE is a white solid and is primarily used as an intermediate in the synthesis of other organic compounds. It may also have applications in pharmaceutical research and as a reagent in chemical reactions. The specific properties and uses of 2,3,4,5-Tetra-O-acetyl-D-ribonitrile may vary depending on the context in which it is being used.

Upstream product

• 58-86-6 D-xylose 
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• 36722-82-4 D-xylose oxime 
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• 1253285-17-4 26-O-β-D-glucopyranosyl-(25R)-5α-furostan-20(22)-en-3β,26-diol-3-O-β-D-xylopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→3)]-β-D-glucopyranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→2)]-β-D-galactopyranoside 
• 1234555-69-1 3β-O-{α-L-rhamnopyranosyl-(1->3)-[β-D-xylopyranose-(1->2)]-β-D-glucopyranosyl-(1->4)-α-L-arabinopyranosyl}-3β-hydroxy-13β,28-epoxy-oleanan-16-oxo-30-al 
• 1392130-57-2 heterobetulinic acid 3-O-β-D-glucopyranosyl(1->2)-β-D-xylopyranoside 
• 50-99-7 D-glucose 
• 608-81-1 D-glucose oxime 
• 1620518-43-5 3-O-β-D-xylopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl-30-norhederagenin 
• 86522-80-7 2,3,4,5-tetra-O-acetyl-D-ribonamide 
• 50-69-1 D-ribose 
• 73713-06-1 amino-ribose 
• 50-69-1 L-Arabinose 

Downstream Products

• 911650-71-0 L-ribo-5-(3.4-dimethyl-anilino)-1.2.3.4-tetraacetoxy-pentane 
• 3051-94-3 3,4-dimethyl-N-ribitylaniline 

Relevant articles and documents

Kinase-Inhibitory Nucleoside Derivatives from the Pacific Bryozoan Nelliella nelliiformis

Marine organisms are a valuable source of bioactive natural products, yet bryozoan invertebrates have been relatively understudied. Herein, we report nelliellosides A and B, new secondary metabolites of the Pacific bryozoan Nelliella nelliiformis, found using NMR-guided isolation. Their structures, including absolute configurations, were elucidated using spectroscopic and chromatographic techniques. Total synthesis of the natural products and four analogues was also achieved, in addition to an assessment of their biological activity, especially kinase inhibition.

A comparative study of the neutral and acidic polysaccharides from Allium macrostemon Bunge

Neutral and acidic polysaccharides, named AMP40N and AMP40S respectively, were isolated and purified from the dried bulbs of Allium macrostemon Bunge. Both of them showed a single and symmetrically sharp peak, indicating they were homogeneous polysaccharides. Molecular weights of AMP40N and AMP40S were determined to be 18.2 and 105.1 kDa, respectively. AMP40N was composed of arabinose and glucose, while AMP40S was composed of rhamnose, arabinose, glucose and galactose and a certain amount of uronic acid. FT-IR, periodic acid oxidation, Smith degradation, methylation and GC-MS analysis revealed that non-reducing terminal and →2,6)-Glc-(1→ existed in AMP40N and AMP40S. The glycosidic linkage of arabinose in AMP40N was →2)-Ara-(1→, whereas it was Ara-(1→ in AMP40S. AMP40S had (1→2)-linked l-rhamnose residue. Both AMP40N and AMP40S exhibited strong anti-tumor potential against human gastric carcinoma cells BGC-823, in particular, AMP40S presented significantly higher inhibitory rate of 85.94% than AMP40N of 52.63%.

New dammarane-type saponins from the roots of panax notoginseng

Three new dammarane-type triterpenoid saponins, 1-3, were isolated and identified as (20S)-20-O-[β-D-xylopyranosyl-(1→6)-β-D- glucopyranosyl-(1→6)-β-D-glucopyranosyl]dammar-24-ene-3β, 6α,12β, 20-tetrol (1), (20S)-6-O-[(E)-but-2-enoyl-(1→6)-β- D-glucopyranosyl]dammar-24-ene-3β,6α,12β,20-tetrol (2), and (20S)-6-O-[β-D-xylopyranosyl-(1→2)-β-D-xylopyranosyl] dammar-24-ene-3β,6α,12β,20-tetrol (3) from the roots of Panax notoginseng (Burkill) F.H.Chen (Araliaceae). Their structures were elucidated on the basis of spectroscopic analyses, including 1D- and 2D-NMR techniques and HR-ESI-MS, as well as by acidic hydrolysis. Copyright