25563-04-6 Usage
Description
2-(4-Chlorophenoxy)phenylacetic acid, also known as 2-(2-(4-Chlorophenoxy)phenyl)acetic acid, is an organic compound with the molecular formula C14H11ClO3. It is a derivative of phenylacetic acid, featuring a chlorophenoxy group attached to the phenyl ring. 2-(4-Chlorophenoxy)phenylacetic acid has potential applications in various fields due to its unique structural properties.
Description
2-(4-Chlorophenoxy)phenylacetic acid is an organic compound derived from phenylacetic acid, featuring a chlorophenoxy group attached to the phenyl ring. It has potential applications in various fields due to its unique structural properties.
Used in Pharmaceutical Industry:
2-(4-Chlorophenoxy)phenylacetic acid is used as a key intermediate for the synthesis of pharmaceutical compounds, serving as a valuable building block for the development of new drugs with specific therapeutic properties.
Used in Alzheimer's Treatment:
2-(4-Chlorophenoxy)phenylacetic acid is used in the preparation of tri-substituted thiazoles as RAGE antagonists for Alzheimer treatments. These compounds are being investigated for their potential to slow down the progression of Alzheimer's disease by modulating the inflammatory response associated with the condition.
Uses
Used in Pharmaceutical Industry:
2-(4-Chlorophenoxy)phenylacetic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a valuable building block for the development of new drugs with specific therapeutic properties.
Used in Alzheimer's Treatment:
In the field of Alzheimer's disease research, 2-(4-Chlorophenoxy)phenylacetic acid is used as a starting material for the preparation of tri-substituted thiazoles. These thiazoles act as RAGE (Receptor for Advanced Glycation End products) antagonists, which are being investigated for their potential to slow down the progression of Alzheimer's disease by modulating the inflammatory response associated with the condition.
By following the format provided in the example, the organized description and uses of 2-(4-Chlorophenoxy)phenylacetic acid are as follows:
Check Digit Verification of cas no
The CAS Registry Mumber 25563-04-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,5,6 and 3 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 25563-04:
(7*2)+(6*5)+(5*5)+(4*6)+(3*3)+(2*0)+(1*4)=106
106 % 10 = 6
So 25563-04-6 is a valid CAS Registry Number.
25563-04-6Relevant articles and documents
Processes for the preparation of 5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole
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Page/Page column 15-16, (2012/07/03)
This invention provides improved processes for the preparation of 5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole, asenapine. These processes allow the preparation of asenapine at industrial scale in good yields and high stereoselectivity.
ASENAPINE MALEATE
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Page/Page column 36, (2012/01/06)
Aspects of the present application relate to a microcrystalline monoclinic form of asenapine maleate represented by structural Formula (I); processes for its preparation; and pharmaceutically acceptable dosage forms thereof.
Design, synthesis and SAR of phenylamino-substituted 5,11-dihydro-dibenzo[a,d]cyclohepten-10-ones and 11H-dibenzo[b,f]oxepin-10-ones as p38 MAP kinase inhibitors
Dorn, Angelika,Schattel, Verena,Laufer, Stefan
scheme or table, p. 3074 - 3077 (2010/07/18)
The p38 MAP kinase is a key enzyme in inflammatory diseases as it is involved in the biosynthesis of proinflammatory cytokines such as TNF-α and IL-1β. Small molecule p38 inhibitors suppress the production of these cytokines and therefore p38 is a promisi
