256390-84-8

Basic information

• Product Name: (S)-4-(hydroxymethyl)-2-phenyl-1,3-dioxane
• Synonyms: (S)-4-(hydroxymethyl)-2-phenyl-1,3-dioxane
• CAS NO: 256390-84-8
• Molecular Weight: 194.23
• Mol File: 256390-84-8.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: (S)-4-(hydroxymethyl)-2-phenyl-1,3-dioxane(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-(hydroxymethyl)-2-phenyl-1,3-dioxane(256390-84-8)
• EPA Substance Registry System: (S)-4-(hydroxymethyl)-2-phenyl-1,3-dioxane(256390-84-8)

Safety Data

• Hazardous Substances Data: 256390-84-8(Hazardous Substances Data)

Upstream product

• 42890-76-6 (S)-1,2,4-butanetriol 
• 100-52-7 benzaldehyde 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 616876-80-3 (S)-2-Phenyl-[1,3]dioxane-4-carboxylic acid (S)-2-phenyl-[1,3]dioxan-4-ylmethyl ester 
• 67-56-1 methanol 
• 32233-43-5 2-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]ethanol 

Downstream Products

• 256390-72-4 (3S)-4-O-hexadecyl-1,3-O-benzylidine-1,3,4-butanetriol 
• 119880-12-5 ethyl (E)-3-((S)-2-phenyl-1,3-dioxan-4-yl)propenoate 
• 1456773-02-6 C₁₃H₁₆O₃ 
• 1456773-03-7 C₂₁H₂₄O₄ 
• 184376-29-2 (S)-3-(benzyloxy)pent-4-en-1-ol 
• 142217-81-0 2-amino-1,9-dihydro-9-[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-6H-purin-6-one 
• 1354715-02-8 (1R,3R,4S)-4-benzyloxy-3-(benzyloxymethyl)-2-methylene-cyclopentanol 
• 139884-80-3 1,3-O-benzylidene-1,3-dihydroxy-4(Z)-pentane 
• 1452390-76-9 C₂₃H₂₁N₅O₃ 
• 1452390-79-2 C₁₆H₁₈N₂O₄ 

Relevant articles and documents

Stereoselective Total Syntheses of Polyacetylene Plant Metabolites via Ester-Tethered Ring Closing Metathesis

Total syntheses of five naturally occurring polyacetylenes from three different plants are described. These natural products have in common an E,Z-configured conjugated diene linked to a di- or triyne chain. As the key method to stereoselectively establis

Design, synthesis, biophysical and primer extension studies of novel acyclic butyl nucleic acid (BuNA)

A novel nucleic acid analogue called acyclic (S)-butyl nucleic acid (BuNA) composed of an acyclic backbone containing a phosphodiester linkage and bearing natural nucleobases was synthesized. Next, (S)-BuNA nucleotides were incorporated in DNA strands and their effect on duplex stability and changes in structural conformation were investigated. Circular dichroism (CD), UV-melting and non-denatured gel electrophoresis (native PAGE) studies revealed that (S)-BuNA is capable of making duplexes with its complementary strands and integration of (S)-BuNA nucleotides into DNA duplex does not alter the B-type-helical structure of the duplex. Furthermore, (S)-BuNA oligonucleotides and (S)-BuNA substituted DNA strands were studied as primer extensions by DNA polymerases. This study revealed that the acyclic scaffold is tolerated by enzymes and is therefore to some extent biocompatible.

Efficient synthesis of the C1-C13 fragment of bistramide A

Herein we report an efficient synthesis of the C1-C13 fragment of bistramide A from (S)-1,2,4-butanetriol and Roche ester in 14 steps and 13% overall yield. Georg Thieme Verlag Stuttgart - New York.