256446-66-9Relevant articles and documents
C26-LINKED RAPAMYCIN ANALOGS AS MTOR INHIBITORS
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Paragraph 00565, (2019/11/21)
The present disclosure relates to mTOR inhibitors. Specifically, the embodiments are directed to compounds and compositions inhibiting mTOR, methods of treating diseases mediated by mTOR, and methods of synthesizing these compounds.
OPTICALLY ACTIVE TRIETHYLENEDIAMINE DERIVATIVE AND METHOD FOR PRODUCING THE SAME
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Paragraph 0108-0110, (2016/12/01)
PROBLEM TO BE SOLVED: To provide an optically active triethylenediamine derivative useful as an asymmetric reagent and a method of producing the same. SOLUTION: An optically active (R or S)-(hydroxymethyl) triethylenediamine represented by formula (1b) (w
FARNESYL PROTEIN TRANSFERASE INHIBITORS
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Page/Page column 31-32, (2010/02/11)
Disclosed are compounds of formula (1.0), wherein R represents a cyclic moiety to which is bound an imodazolylalkyl group; R represents a carbamate, urea, amide or sulfonamide group; and the remaining substituents are as defined herein. Also disclosed is a method of treating cancer and a method of inhibiting farnesyl protein transferase using the disclosed compounds.