256461-49-1

Basic information

• Product Name: 1-[(2S,3R)-2-benzyloxy-5-(2,3-dichlorophen-1-yl)-3-pentyl]imidazole-4-carboxamide
• Synonyms: 1-[(2S,3R)-2-benzyloxy-5-(2,3-dichlorophen-1-yl)-3-pentyl]imidazole-4-carboxamide
• CAS NO: 256461-49-1
• Molecular Weight: 432.35
• Mol File: 256461-49-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-[(2S,3R)-2-benzyloxy-5-(2,3-dichlorophen-1-yl)-3-pentyl]imidazole-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(2S,3R)-2-benzyloxy-5-(2,3-dichlorophen-1-yl)-3-pentyl]imidazole-4-carboxamide(256461-49-1)
• EPA Substance Registry System: 1-[(2S,3R)-2-benzyloxy-5-(2,3-dichlorophen-1-yl)-3-pentyl]imidazole-4-carboxamide(256461-49-1)

Safety Data

• Hazardous Substances Data: 256461-49-1(Hazardous Substances Data)

Upstream product

• 26832-08-6 imidazole-4-carboxamide 
• 256462-66-5 (3S)-3-benzyloxy-1,2-epoxybutane 
• 3290-01-5 2,3-dichlorobenzyl chloride 
• 256462-13-2 (2S,3S)-2-benzyloxy-5-(2,3-dichlorophen-1-yl)pentan-3-ol 

Downstream Products

• 256461-93-5 1-[(2S,3R)-2-hydroxy-5-(2,3-dichlorophenyl)-3-pentyl]-imidazole-4-carboxamide 

Relevant articles and documents

Structure-based design and synthesis of non-nucleoside, potent, and orally bioavailable adenosine deaminase inhibitors

We disclose optimization efforts based on the novel non-nucleoside adenosine deaminase (ADA) inhibitor, 4 (Ki = 680 nM). Structure-based drug design utilizing the crystal structure of the 4/ADA complex led to discovery of 5 (Ki = 11