256499-19-1 Usage
Description
1-(2-Fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride is a chemical compound that serves as a crucial intermediate in the synthesis of Riociguat, a medication used for the treatment of pulmonary hypertension. 1-(2-Fluoro-benzyl)-1H-py... plays a significant role in the development of pharmaceuticals targeting cardiovascular diseases.
Uses
Used in Pharmaceutical Industry:
1-(2-Fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride is used as a key intermediate for the synthesis of Riociguat, a potent oral stimulator of soluble guanylate cyclase. Riociguat is specifically designed for the treatment of pulmonary hypertension, a severe and life-threatening condition characterized by high blood pressure in the arteries of the lungs. The compound contributes to the development of innovative therapies for patients suffering from this disease.
Check Digit Verification of cas no
The CAS Registry Mumber 256499-19-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,6,4,9 and 9 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 256499-19:
(8*2)+(7*5)+(6*6)+(5*4)+(4*9)+(3*9)+(2*1)+(1*9)=181
181 % 10 = 1
So 256499-19-1 is a valid CAS Registry Number.
256499-19-1Relevant articles and documents
PROCESS FOR THE PREPARATION OF METHYL 4,6-DIAMINO-2-[L-(2-FHIOROBENZVR)-LH-PYRAZOLO I3,4-BLPVRIDIN-3-VN-5-PYRIMIDINYL(METHVL)CARBAMATE AND ITS POLYMORPHS THEREOF
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Page/Page column 33; 34, (2017/03/08)
The present invention relates to process for the preparation of methyl 4,6-diamino-2-[1-(2-fluorobenzyl)-lH-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl(methyl)carbamate and its polymorphs thereof compound of formula-1, represented by the following structur
PYRIDINE-SUBSTITUTED PYRAZOLOPYRIDINE DERIVATIVE
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Page/Page column 13-14, (2010/02/06)
The invention relates to a substituted pyrazole derivative and the use thereof as a medicament, particularly as a medicament for treating cardiovascular diseases.