25650-54-8

Basic information

• Product Name: Benzene, 1-chloro-4-[2-(methylsulfonyl)ethenyl]-, (E)-
• CAS NO: 25650-54-8
• Molecular Formula: C9H9ClO2S
• Molecular Weight: 216.688
• Mol File: 25650-54-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzene, 1-chloro-4-[2-(methylsulfonyl)ethenyl]-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-chloro-4-[2-(methylsulfonyl)ethenyl]-, (E)-(25650-54-8)
• EPA Substance Registry System: Benzene, 1-chloro-4-[2-(methylsulfonyl)ethenyl]-, (E)-(25650-54-8)

Safety Data

• Hazardous Substances Data: 25650-54-8(Hazardous Substances Data)

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 1615-02-7 3-(4-chlorophenyl)prop-2-enoic acid 
• 706-07-0 1-chloro-4-(2-nitrovinyl)benzene 
• 23265-32-9 1-(methylsulfonyl)-2-(phenyl)diazene 
• 1073-67-2 4-vinylbenzyl chloride 
• 110-05-4 di-tert-butyl peroxide 
• 20277-69-4 sodium methansulfinate 
• 873-73-4 4-n-chlorophenylacetylene 
• 67-68-5 dimethyl sulfoxide 
• 66482-29-9 1-[(E)-2-bromoethenyl]-4-chlorobenzene 
• 76896-97-4 (E)-3-(4-Chloro-phenyl)-2-methanesulfonyl-acrylic acid ethyl ester 
• 2516-97-4 2-(methylsulfonyl)acetic acid 

Downstream Products

• 37630-45-8 cis-β-(4-Chlor-styryl)-methyl-sulfon 

Relevant articles and documents

A photocatalyst-free visible-light-mediated solvent-switchable route to stilbenes/vinyl sulfones from β-nitrostyrenes and arylazo sulfones

Photocatalyst-free visible-light-mediated reactions, based on the presence of a visible-light-absorbing functional group in the starting material itself in order to exclude the often costly, hazardous, degradable and difficult to remove or recover photoredox catalysts, have been gaining momentum recently. We have employed this approach to develop a denitrative photocatalyst-free visible-light-mediated protocol for the arylation/sulfonylation of β-nitrostyrenes employing arylazo sulfones (bench-stable photolabile compounds) in a switchable solvent-controlled manner. Arylazo sulfones served as the aryl and sulfonyl radical precursors under blue LED irradiation for the synthesis oftrans-stilbenes and (E)-vinyl sulfones in CH3CN and dioxane/H2O 2?:?1, respectively. The absence of any metal, photocatalyst and additive; excellent selectivity (E-stereochemistry) and solvent-switchability; and the use of visible light and ambient temperature are the prime assets of the developed method. Moreover, we report the first photocatalyst-free visible light-driven route to synthesize stilbenes and vinyl sulfones from readily available β-nitrostyrenes.

Direct C-H Methylsulfonylation of Alkenes with the Insertion of Sulfur Dioxide

The direct C-H methylsulfonylation of alkenes using inorganic sodium metabisulfite as the sulfur dioxide surrogate is described. This method provides convenient access to (E)-2-methyl styrenyl sulfones in good yields. In general, the in situ generated met

CuSO4?·5H2O-H-phosphonate-catalyzed intermolecular C-S bond formation: Synthesis of (E)-vinyl alkylsulfones from alkynes and DMSO

A CuSO4?·5H2O-H-phosphonate-catalyzed synthesis of (E)-vinyl alkylsulfones from alkynes and widely available DMSO was developed. The present protocol provides an alternative approach to various vinyl sulfones, with the advantages of cheap catalysts, readily available starting materials, operational simplicity and high stereo- and regioselectivity.